Record in detail


General Info

  • lamp_id:L01A003376
  • Name:GLL4_CHICK
  • FullName:Gallinacin-4
  • Source:Gallus gallus
  • Mass:4428.2 Da
  • Sequence Length:38 aa
  • Isoelectric Point:9.11
  • Activity:Antibacterial
  • Sequence
        RYHMQCGYRGTFCTPGKCPHGNAYLGLCRPKYSCCRWL
  • Function:Has bactericidal activity. Potent activity against S.typhimurium and S.entiriditis.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A07923|    From 26 To 63 E-value: 1e-18 Score: 83.6
        RYHMQCGYRGTFCTPGKCPHGNAYLGLCRPKYSCCRWL
  • 2. L01A003376    From 1 To 38 E-value: 6e-18 Score: 81.3
        RYHMQCGYRGTFCTPGKCPHGNAYLGLCRPKYSCCRWL
  • 3. L13A022536    From 1 To 37 E-value: 2e-17 Score: 79.3
        RYHMQCGYRGTFCTPGKCPHGNAYLGLCRPKYSCCRW
  • 4. L02A000743    From 1 To 38 E-value: 2e-17 Score: 79.3
        RYHMQCGYRGTFCTPGKCPYGNAYLGLCRPKYSCCRWL
  • 5. L13A022870    From 1 To 37 E-value: 8e-17 Score: 77.4
        RYHMQCGYRGTFCTPGKCPYGNAYLGLCRPKYSCCRW

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Cheng J.-F.,Matsuda Y.,Ando J.,Hughes A.L.,Xiao Y.,
  •   Title:A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins.
  •   Journal:BMC Genomics, 2004, 5, 56-56  [PubMed:15310403]
  •   [2]  James T.,Tierney J.,Gaines S.,Higgs R.,Lynn D.J.,
  •   Title:Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken.
  •   Journal:Immunogenetics, 2004, 56, 170-177  [PubMed:15148642]
  •   [3]  Yoshimura Y.,Nishibori M.,Isobe N.,Subedi K.,
  •   Title:Changes in the expression of gallinacins, antimicrobial peptides, in ovarian follicles during follicular growth and in response to lipopolysaccharide in laying hens (Gallus domesticus).
  •   Journal:Reproduction, 2007, 133, 127-133  [PubMed:17244739]
  •   [4]  Hall J.,Bevan R.M.,Townes C.L.,Milona P.,
  •   Title:The chicken host peptides, gallinacins 4, 7, and 9 have antimicrobial activity against Salmonella serovars.
  •   Journal:Biochem. Biophys. Res. Commun., 2007, 356, 169-174  [PubMed:17346671]

Comments

  •   Comments

  •     No comments found on LAMP database



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