Record in detail
General Info
- lamp_id:L01A003376
- Name:GLL4_CHICK
- FullName:Gallinacin-4
- Source:Gallus gallus
- Mass:4428.2 Da
- Sequence Length:38 aa
- Isoelectric Point:9.11
- Activity:Antibacterial
- Sequence
RYHMQCGYRGTFCTPGKCPHGNAYLGLCRPKYSCCRWL - Function:Has bactericidal activity. Potent activity against S.typhimurium and S.entiriditis.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1080
- 2 Database:dbAMP dbAMP_10883
- 3 Database:DRAMP DRAMP03652
- 4 Database:SATPdb satpdb18525
- 5 Database:Uniprot Q6GXJ1
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A07923| From 26 To 63 E-value: 1e-18 Score: 83.6
RYHMQCGYRGTFCTPGKCPHGNAYLGLCRPKYSCCRWL - 2. L01A003376 From 1 To 38 E-value: 6e-18 Score: 81.3
RYHMQCGYRGTFCTPGKCPHGNAYLGLCRPKYSCCRWL - 3. L13A022536 From 1 To 37 E-value: 2e-17 Score: 79.3
RYHMQCGYRGTFCTPGKCPHGNAYLGLCRPKYSCCRW - 4. L02A000743 From 1 To 38 E-value: 2e-17 Score: 79.3
RYHMQCGYRGTFCTPGKCPYGNAYLGLCRPKYSCCRWL - 5. L13A022870 From 1 To 37 E-value: 8e-17 Score: 77.4
RYHMQCGYRGTFCTPGKCPYGNAYLGLCRPKYSCCRW
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Cheng J.-F.,Matsuda Y.,Ando J.,Hughes A.L.,Xiao Y.,
- Title:A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins.
- Journal:BMC Genomics, 2004, 5, 56-56 [PubMed:15310403]
- [2] James T.,Tierney J.,Gaines S.,Higgs R.,Lynn D.J.,
- Title:Bioinformatic discovery and initial characterisation of nine novel antimicrobial peptide genes in the chicken.
- Journal:Immunogenetics, 2004, 56, 170-177 [PubMed:15148642]
- [3] Yoshimura Y.,Nishibori M.,Isobe N.,Subedi K.,
- Title:Changes in the expression of gallinacins, antimicrobial peptides, in ovarian follicles during follicular growth and in response to lipopolysaccharide in laying hens (Gallus domesticus).
- Journal:Reproduction, 2007, 133, 127-133 [PubMed:17244739]
- [4] Hall J.,Bevan R.M.,Townes C.L.,Milona P.,
- Title:The chicken host peptides, gallinacins 4, 7, and 9 have antimicrobial activity against Salmonella serovars.
- Journal:Biochem. Biophys. Res. Commun., 2007, 356, 169-174 [PubMed:17346671]
Comments
- Comments
No comments found on LAMP database