Record in detail


General Info

  • lamp_id:L01A003378
  • Name:HEPC1_SALSA
  • FullName:Hepcidin-1
  • Source:Salmo salar
  • Mass:2720.3 Da
  • Sequence Length:25 aa
  • Isoelectric Point:7.66
  • Activity:Antimicrobial
  • Sequence
        QIHLSLCGLCCNCCHNIGCGFCCKF
  • Function:Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages. May also have antimicrobial activity (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003378    From 1 To 25 E-value: 0.00000002 Score: 49.7
        QIHLSLCGLCCNCCHNIGCGFCCKF
  • 2. L12A07597|    From 64 To 88 E-value: 0.0000005 Score: 45.1
        QSHLSLCRWCCNCCHNKGCGFCCKF
  • 3. L12A07596|    From 64 To 88 E-value: 0.0000005 Score: 45.1
        QSHLSLCRWCCNCCHNKGCGFCCKF
  • 4. L12A07592|    From 61 To 85 E-value: 0.000001 Score: 43.9
        QSHLSLCRWCCKCCHNKGCGFCCKF
  • 5. L12A07598|    From 64 To 88 E-value: 0.000003 Score: 42.4
        QSHLSLCRWCRNCCHNKGCGFCCKF

Structure

  •   Domains
  •   1  Name:Hepcidin    Interpro Link:IPR010500
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Tsoi S.C.M.,Dacanay A.,Liebscher R.S.,Gallant J.W.,Douglas S.E.,
  •   Title:Identification and expression analysis of hepcidin-like antimicrobial peptides in bony fish.
  •   Journal:Dev. Comp. Immunol., 2003, 27, 589-601  [PubMed:12697315]

Comments

  •   Comments

    •     No comments found on LAMP database



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