Record in detail


General Info

  • lamp_id:L01A003380
  • Name:BR2PC_RANPC
  • FullName:Brevinin-2PTc
  • Source:Rana picturata
  • Mass:3425.1 Da
  • Sequence Length:33 aa
  • Isoelectric Point:10.14
  • Activity:Antibacterial
  • Sequence
        GLLDSFKNAMIGIAKSAGKTALNKIACKIDKTC
  • Function:Has antibacterial activity against the Gram-positive bacterium S.aureus ATCC 25923 (MIC>72uM) and the Gram-negative bacterium E.coli ATCC 25726 (MIC=18uM).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003380    From 1 To 33 E-value: 0.0000000000003 Score: 65.5
        GLLDSFKNAMIGIAKSAGKTALNKIACKIDKTC
  • 2. L01A003303    From 1 To 33 E-value: 0.000000000006 Score: 61.2
        GFLDSFKNAMIGVAKSAGKTALNTLACKIDKTC
  • 3. L01A003302    From 1 To 33 E-value: 0.0000000001 Score: 56.6
        GFLDSFKNAMIGVAKSVGKTALSTLACKIDKSC
  • 4. L01A003381    From 1 To 33 E-value: 0.00000003 Score: 49.3
        GFKGAFKNVMFGIAKSAGKSALNALACKIDKSC
  • 5. L12A07302|    From 44 To 76 E-value: 0.000001 Score: 43.9
        GLLDTLKNVAIGVAKGAGVGVLNALSCKLDKSC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities
  •   1  Target:  S.aureus ATCC 25923  MIC:  246.61 μg/ml  (72.0008 μM)  
  •   2  Target:  E.coli ATCC 25726  MIC:  61.65 μg/ml  (17.9995 μM)  
  •   3  Target:  E. coli  MIC:  61.6518 μg/ml  (18 μM)  
  •   4  Target:  S. aureus  MIC:  246.607 μg/ml  (72 μM)  

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Vaudry H.,Leprince J.,Nowotny N.,Kolodziejek J.,Conlon J.M.,
  •   Title:Characterization of antimicrobial peptides from the skin secretions of the Malaysian frogs, Odorrana hosii and Hylarana picturata (Anura:Ranidae).
  •   Journal:Toxicon, 2008, 52, 465-473  [PubMed:18621071]

Comments

  •   Comments

    •     No comments found on LAMP database



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