Record in detail
General Info
- lamp_id:L01A003381
- Name:BR2PB_RANPC
- FullName:Brevinin-2PTb
- Source:Rana picturata
- Mass:3377 Da
- Sequence Length:33 aa
- Isoelectric Point:10.51
- Activity:Antibacterial
- Sequence
GFKGAFKNVMFGIAKSAGKSALNALACKIDKSC - Function:Has antibacterial activity against the Gram-positive bacterium S.aureus ATCC 25923 (MIC=9uM) and the Gram-negative bacterium E.coli ATCC 25726 (MIC=9uM).
Cross-Linking
- Cross-linking
- 1 Database:APD 1428
- 2 Database:CAMP CAMPSQ1083
- 3 Database:DBAASP 2223
- 4 Database:dbAMP dbAMP_02613
- 5 Database:DRAMP DRAMP01956
- 6 Database:SATPdb satpdb27232
- 7 Database:Uniprot P0C8T4
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A003381 From 1 To 33 E-value: 0.0000000000005 Score: 64.7
GFKGAFKNVMFGIAKSAGKSALNALACKIDKSC - 2. L01A003303 From 1 To 33 E-value: 0.000000003 Score: 52
GFLDSFKNAMIGVAKSAGKTALNTLACKIDKTC - 3. L01A003302 From 1 To 33 E-value: 0.00000002 Score: 49.7
GFLDSFKNAMIGVAKSVGKTALSTLACKIDKSC - 4. L01A003380 From 1 To 33 E-value: 0.00000003 Score: 49.3
GLLDSFKNAMIGIAKSAGKTALNKIACKIDKTC - 5. L12A07302| From 44 To 76 E-value: 0.000005 Score: 41.6
GLLDTLKNVAIGVAKGAGVGVLNALSCKLDKSC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: S.aureus ATCC 25923 MIC: 30.39 μg/ml (8.99911 μM)
- 2 Target: E.coli ATCC 25726 MIC: 30.39 μg/ml (8.99911 μM)
- 3 Target: E. coli MIC: 30.393 μg/ml (9 μM)
- 4 Target: S. aureus MIC: 30.393 μg/ml (9 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Vaudry H.,Leprince J.,Nowotny N.,Kolodziejek J.,Conlon J.M.,
- Title:Characterization of antimicrobial peptides from the skin secretions of the Malaysian frogs, Odorrana hosii and Hylarana picturata (Anura:Ranidae).
- Journal:Toxicon, 2008, 52, 465-473 [PubMed:18621071]
Comments
- Comments
No comments found on LAMP database