Record in detail
General Info
- lamp_id:L01A003382
- Name:BR2PA_RANPC
- FullName:Brevinin-2PTa
- Source:Rana picturata
- Mass:3129.8 Da
- Sequence Length:30 aa
- Isoelectric Point:10.06
- Activity:Antibacterial
- Sequence
GAIKDALKGAAKTVAVELLKKAQCKLEKTC - Function:Has antibacterial activity against the Gram-positive bacterium S.aureus ATCC 25923 (MIC=18uM) and the Gram-negative bacterium E.coli ATCC 25726 (MIC=18uM).
Cross-Linking
- Cross-linking
- 1 Database:APD 1427
- 2 Database:CAMP CAMPSQ1084
- 3 Database:DBAASP 2222
- 4 Database:dbAMP dbAMP_02425
- 5 Database:DRAMP DRAMP01955
- 6 Database:SATPdb satpdb13113
- 7 Database:Uniprot P0C8T3
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A003382 From 1 To 30 E-value: 0.0000000001 Score: 57
GAIKDALKGAAKTVAVELLKKAQCKLEKTC - 2. L01A000100 From 1 To 30 E-value: 0.0000004 Score: 45.4
GVITDALKGAAKTVAAELLRKAHCKLTNSC - 3. L12A07325| From 43 To 72 E-value: 0.0000004 Score: 45.4
GVITDALKGAAKTVAAELLRKAHCKLTNSC - 4. L07APD0160 From 1 To 30 E-value: 0.000002 Score: 43.1
GVIIDTLKGAAKTVAAELLRKAHCKLTNSC - 5. L13A020468 From 1 To 30 E-value: 0.0006 Score: 34.7
GAFTDLLKGVAKQAGIKILGIAQCKLAKTC
Structure
- Domains
- 1 Name:Antimicrobial_frog_2 Interpro Link:IPR012521
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
- 1 Target: S.aureus ATCC 25923 MIC: 56.34 μg/ml (18.0012 μM)
- 2 Target: E.coli ATCC 25726 MIC: 56.34 μg/ml (18.0012 μM)
- 3 Target: E. coli MIC: 56.3364 μg/ml (18 μM)
- 4 Target: S. aureus MIC: 56.3364 μg/ml (18 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Vaudry H.,Leprince J.,Nowotny N.,Kolodziejek J.,Conlon J.M.,
- Title:Characterization of antimicrobial peptides from the skin secretions of the Malaysian frogs, Odorrana hosii and Hylarana picturata (Anura:Ranidae).
- Journal:Toxicon, 2008, 52, 465-473 [PubMed:18621071]
Comments
- Comments
No comments found on LAMP database