Record in detail
General Info
- lamp_id:L01A003422
- Name:DFA14_MOUSE
- FullName:Alpha-defensin 14
- Source:Mus musculus
- Mass:4227.1 Da
- Sequence Length:35 aa
- Isoelectric Point:10.28
- Activity:Antimicrobial
- Sequence
LRDLVCYCRTRGCKRRERMNGTCRKGHLMHTLCCR - Function:Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1848
- 2 Database:dbAMP dbAMP_05993
- 3 Database:DRAMP DRAMP03341
- 4 Database:Uniprot P50712
- 5 Database:DEF DEF237
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000003 From 51 To 85 E-value: 3e-16 Score: 75.5
LRDLVCYCRTRGCKRRERMNGTCRKGHLMHTLCCR - 2. L03A000165 From 59 To 93 E-value: 0.000000000000001 Score: 73.2
LRDLVCYCRTRGCKRRERMNGTCRKGHLMYTLCCR - 3. L12A08327| From 59 To 93 E-value: 0.000000000000003 Score: 72
LRDLVCYCRTRGCKRRERMNGTCRKGHLIYTLCCR - 4. L03A000176 From 59 To 93 E-value: 0.000000000000005 Score: 71.2
LRDLVCYCRTRGCKRREHMNGTCRKGHLMYTLCCR - 5. L03A000182 From 59 To 93 E-value: 0.000000000000006 Score: 71.2
LRDLVCYCRKRGCKRRERMNGTCRKGHLMYTLCCR
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Huttner K.M.,Cano-Gauci D.F.,Nosek M.T.,Hsieh M.M.,Ouellette A.J.,
- Title:Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.
- Journal:Infect. Immun., 1994, 62, 5040-5047 [MEDLINE:95012724]
- [2] Ouellette A.J.,Selsted M.E.,Huttner K.M.,
- Title:Structure and diversity of the murine cryptdin gene family.
- Journal:Genomics, 1994, 19, 448-453 [MEDLINE:94245232]
Comments
- Comments
No comments found on LAMP database