Record in detail


General Info

  • lamp_id:L01A003424
  • Name:DFA11_MOUSE
  • FullName:Alpha-defensin 11
  • Source:Mus musculus
  • Mass:4152 Da
  • Sequence Length:35 aa
  • Isoelectric Point:9.57
  • Activity:Antimicrobial
  • Sequence
        LRDLVCYCRSRGCKGRERMNGTCRKGHLLYMLCCR
  • Function:Probably contributes to the antimicrobial barrier function of the small bowel mucosa.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000004    From 51 To 85 E-value: 3e-16 Score: 75.5
        LRDLVCYCRSRGCKGRERMNGTCRKGHLLYMLCCR
  • 2. L03A000177    From 59 To 93 E-value: 6e-16 Score: 74.7
        LRDLVCYCRARGCKGRERMNGTCRKGHLLYMLCCR
  • 3. L03A000156    From 59 To 93 E-value: 0.000000000000001 Score: 73.2
        LRDLVCYCRSRGCKGRERMNGTCRKGHLLYTLCCR
  • 4. L03A000178    From 59 To 93 E-value: 0.000000000000002 Score: 72.8
        LRDLVCYCRSRGCKGRERMNGTCRKGHLMYTLCCR
  • 5. L12A08317|    From 59 To 93 E-value: 0.000000000000002 Score: 72.8
        LRDLVCYCRARGCKGRERMNGTCSKGHLLYMLCCR

Structure

  •   Domains
  •   1  Name:Alpha-defensin    Interpro Link:IPR016327
  •   2  Name:Defensin_beta/neutrophil    Interpro Link:IPR006080
  •   3  Name:Defensin_propep    Interpro Link:IPR002366
  •   4  Name:Mammalian_defensins    Interpro Link:IPR006081
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Huttner K.M.,Cano-Gauci D.F.,Nosek M.T.,Hsieh M.M.,Ouellette A.J.,
  •   Title:Mouse Paneth cell defensins: primary structures and antibacterial activities of numerous cryptdin isoforms.
  •   Journal:Infect. Immun., 1994, 62, 5040-5047  [MEDLINE:95012724]
  •   [2]  Ouellette A.J.,Selsted M.E.,Huttner K.M.,
  •   Title:Structure and diversity of the murine cryptdin gene family.
  •   Journal:Genomics, 1994, 19, 448-453  [MEDLINE:94245232]

Comments

  •   Comments

    •     No comments found on LAMP database



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