Record in detail
General Info
- lamp_id:L01A003428
- Name:CT111_LACTA
- FullName:M-zodatoxin-Lt8h
- Source:Lachesana tarabaevi
- Mass:7885.4 Da
- Sequence Length:69 aa
- Isoelectric Point:10.91
- Activity:Antibacterial
- Sequence
GFFGNAWKKIKGKAEKFFRKKAAKIIAKKEGITKEEAEAKVDTMSKKQIKVYLLKHYGKKALQKASEKL - Function:Insecticidal, cytolytic and antimicrobial peptide. Has insecticidal activity against the flesh fly S.carnaria. Has antibacterial activity against the Gram-negative bacteria E.coli. Forms voltage-dependent, ion-permeable channels in membranes. At high concentration causes cell membrane lysis.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1854
- 2 Database:dbAMP dbAMP_02518
- 3 Database:DRAMP DRAMP03243
- 4 Database:Uniprot P85247
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A003428 From 1 To 69 E-value: 1e-32 Score: 129
GFFGNAWKKIKGKAEKFFRKKAAKIIAKKEGITKEEAEAKVDTMSKKQIKVYLLKHYGKKALQKASEKL - 2. L01A003853 From 1 To 69 E-value: 6e-32 Score: 127
GFFGNAWKKIKGKAEKFFRKKAAKIIAKKEGITKEEAEAKVDPMSKKQIKVYLLKHYGKKALQKASEKL - 3. L01A003430 From 1 To 69 E-value: 1e-26 Score: 109
GFFGNTWKKIKGKADKIMLKKAVKIMVKKEGISKEEAQAKVDAMSKKQIRLYLLKHYGKKALQKASEKL - 4. L01A003432 From 1 To 69 E-value: 3e-26 Score: 108
GFFGNTWKKIKGKADKIMLKKAVKIMVKKEGITKEEAQAKVDAMSKKQIRLYLLKYYGKKALQKASEKL - 5. L01A003847 From 1 To 69 E-value: 3e-26 Score: 108
GFFGNTWKKIKGKTDKIMLKKAVKIMVKKEGISKEEAQAKVDAMSKKQIRLYLLKHYGKKALQKASEKL
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Karpunin D.V.,Egorova N.S.,Samsonova O.V.,Kozlov S.A.,Vassilevski A.A.,
- Title:Cyto-insectotoxins, a novel class of cytolytic and insecticidal peptides from spider venom.
- Journal:Biochem. J., 2008, 411, 687-696 [PubMed:18215128]
Comments
- Comments
No comments found on LAMP database