Record in detail
General Info
- lamp_id:L01A003450
- Name:SPG11_MOUSE
- FullName:Sperm-associated antigen 11
- Source:Mus musculus
- Mass:5952.9 Da
- Sequence Length:52 aa
- Isoelectric Point:8.63
- Activity:Antibacterial
- Sequence
PGDIPPGIRNTVCLMQQGHCRLFMCRSGERKGDICSDPWNRCCVPYSVKDRR - Function:Antimicrobial peptide against E.coli. Is also responsible for sperm maturation, storage, and protection (By similarity).
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1875
- 2 Database:dbAMP dbAMP_09914
- 3 Database:DRAMP DRAMP03399
- 4 Database:Uniprot Q8K4N2
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A003450 From 1 To 52 E-value: 1e-26 Score: 109
PGDIPPGIRNTVCLMQQGHCRLFMCRSGERKGDICSDPWNRCCVPYSVKDRR - 2. L13A012265 From 1 To 50 E-value: 1e-25 Score: 106
PGDIPPGIRNTVCLMQQGHCRLFMCRSGERKGDICSDPWNRCCVPYSVKD - 3. L03A000186 From 19 To 68 E-value: 6e-23 Score: 97.8
GDIPPGIRNTVCFMQRGHCRLFMCRSGERKGDICSDPWNRCCVSSSIKNR - 4. L01A003362 From 1 To 49 E-value: 7e-22 Score: 94.4
DIPPGIRNTVCFMQRGHCRLFMCRSGERKGDICSDPWNRCCVSSSIKNR - 5. L12A08375| From 19 To 69 E-value: 5e-20 Score: 88.2
GDVPPGIRNIICLMQHGTCRLFFCRSGEKKSEICSDPWNRCCIPHSEEERK
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Tomita T.,Fukuhara S.,Makita R.,Nagase T.,Yamaguchi Y.,
- Title:Identification of multiple novel epididymis-specific beta-defensin isoforms in humans and mice.
- Journal:J. Immunol., 2002, 169, 2516-2523 [MEDLINE:22181517]
- [2] Zhang G.,Blecha F.,Sang Y.,Cai Y.,Patil A.A.,
- Title:Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
- Journal:Physiol. Genomics, 2005, 23, 5-17 [PubMed:16033865]
- [3] Frith M.C.,Gough J.,Katayama S.,Kasukawa T.,Carninci P.,
- Title:The transcriptional landscape of the mammalian genome.
- Journal:Science, 2005, 309, 1559-1563 [PubMed:16141072]
Comments
- Comments
No comments found on LAMP database