Record in detail

lamp_id:L01A003459
Name:LANPA_PAEPO
FullName:Lantibiotic paenibacillin
Source:Paenibacillus polymyxa
Mass:3105.7 Da
Sequence Length:30 aa
Isoelectric Point:9.16
Activity:Antibacterial
Sequence
ASIIKTTIKVSKAVCKTLTCICTGSCSNCK
Function:Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores. Lacks antibacterial activity against Gram-negative bacteria.

Top similar AMPs on LAMP
1. L12A08363| From 24 To 53 E-value: 0.00000000008 Score: 57.8
ASIIKTTIKVSKAVCKTLTCICTGSCSNCK
2. L01A003459 From 1 To 30 E-value: 0.0000000004 Score: 55.5
ASIIKTTIKVSKAVCKTLTCICTGSCSNCK
3. L11A013046 From 1 To 30 E-value: 0.00001 Score: 40
AXIIKXXIKVXKAVCKXLXCICXGXCXNCK
4. L12A12119| From 3 To 27 E-value: 0.00004 Score: 38.9
TIVKVSKAVCKTGTCICTTSCSNCK
5. L12A07943| From 26 To 49 E-value: 0.044 Score: 28.5
ASIVKTTIKASKKLCRGFTLTCGC

Reference
[1] Green-Church K.B.,Yuan C.,Zhang L.,Kisla D.,He Z.,
Title:Isolation and identification of a Paenibacillus polymyxa strain that coproduces a novel lantibiotic and polymyxin.
Journal:Appl. Environ. Microbiol., 2007, 73, 168-178 [PubMed:17071789]
[2] Yousef A.E.,Zhang L.,Yuan C.,He Z.,
Title:N-terminal acetylation in paenibacillin, a novel lantibiotic.
Journal:FEBS Lett., 2008, 582, 2787-2792 [PubMed:18625234]