Record in detail
General Info
- lamp_id:L01A003467
- Name:GRA3_POGPU
- FullName:Grammistin Pp 3
- Source:Pogonoperca punctata
- Mass:2587 Da
- Sequence Length:25 aa
- Isoelectric Point:9.3
- Activity:Antibacterial
- Sequence
NWRKILGQIASVGAGLLGSLLAGYE - Function:Thanks to its abundant amphiphilic alpha-helices, it may integrate into membrane phospholipids, leading to lysis of the membrane. Has hemolytic activity. Has antibacterial activity with a broad spectrum against various species of bacteria including both Gram-positive and Gram-negative groups. Has also ichthyotoxic activity.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1094
- 2 Database:DBAASP 3337
- 3 Database:dbAMP dbAMP_09840
- 4 Database:DRAMP DRAMP02321
- 5 Database:SATPdb satpdb25103
- 6 Database:Uniprot P69847
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A003467 From 1 To 25 E-value: 0.00000002 Score: 49.7
NWRKILGQIASVGAGLLGSLLAGYE - 2. L01A003529 From 1 To 25 E-value: 0.000001 Score: 43.5
NWRKILGKIAKVAAGLLGSMLAGYQ - 3. L01A003530 From 2 To 25 E-value: 0.57 Score: 24.6
WRELLKKLAFTAAGHLGSVLAAKQ - 4. L13A019107 From 2 To 13 E-value: 4.1 Score: 21.9
NWKKILGKIKKV - 5. L13A023444 From 2 To 13 E-value: 4.8 Score: 21.6
NWRRILGRIIRV
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Shiomi K.,Nagashima Y.,Yokota H.,
- Title:Interaction of grammistins with lipids and their antibacterial activity.
- Journal:Fish. Sci., 2001, 67, 928-933 [DOI:10.1046/j.1444-2906.2001.00343.x]
- [2] Ishida M.,Nagashima Y.,Yokota H.,Shiomi K.,
- Title:Primary and secondary structures of grammistins, peptide toxins isolated from the skin secretion of the soapfish Pogonoperca punctata.
- Journal:Fish. Sci., 2001, 67, 163-169 [DOI:10.1046/j.1444-2906.2001.00213.x]
Comments
- Comments
No comments found on LAMP database