Record in detail


General Info

  • lamp_id:L01A003484
  • Name:HEPC_PONAB
  • FullName:Hepcidin
  • Source:Pongo abelii
  • Mass:2857.4 Da
  • Sequence Length:25 aa
  • Isoelectric Point:8.05
  • Activity:Antimicrobial
  • Sequence
        DTHFPIYIFCCGCCHRSKCGMCCKT
  • Function:Seems to act as a signaling molecule involved in the maintenance of iron homeostasis. Seems to be required in conjunction with HFE to regulate both intestinal iron absorption and iron storage in macrophages (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003484    From 1 To 25 E-value: 0.000000001 Score: 53.5
        DTHFPIYIFCCGCCHRSKCGMCCKT
  • 2. L12A06333|    From 60 To 84 E-value: 0.000000002 Score: 52.8
        DTHFPICIFCCGCCHRSKCGMCCKT
  • 3. L12A06331|    From 61 To 85 E-value: 0.000000002 Score: 52.8
        DTHFPICIFCCGCCHRSKCGMCCKT
  • 4. L01A001835    From 60 To 84 E-value: 0.000000002 Score: 52.8
        DTHFPICIFCCGCCHRSKCGMCCKT
  • 5. L12A08786|    From 57 To 81 E-value: 0.000000004 Score: 52
        DTHFPICMFCCGCCHRSKCGMCCKT

Structure

  •   Domains
  •   1  Name:Hepcidin    Interpro Link:IPR010500
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference

    •     No references found on LAMP database

Comments

  •   Comments

    •     No comments found on LAMP database



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