Record in detail


General Info

  • lamp_id:L01A003486
  • Name:HEPC2_MOUSE
  • FullName:Hepcidin-2
  • Source:Mus musculus
  • Mass:2829.3 Da
  • Sequence Length:25 aa
  • Isoelectric Point:4.42
  • Activity:Antimicrobial
  • Sequence
        DINFPICRFCCQCCNKPSCGICCEE
  • Function:Seems to act as a signaling molecule involved in the maintenance of iron homeostasis (By similarity).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003127    From 31 To 54 E-value: 0.000000003 Score: 52
        DINFPICRFCCQCCNKPSCGICCE
  • 2. L01A003486    From 1 To 25 E-value: 0.000000006 Score: 51.2
        DINFPICRFCCQCCNKPSCGICCEE
  • 3. L12A09469|    From 59 To 81 E-value: 0.00001 Score: 40
        DTHFPVCHFCCNCCSKPGCGICC
  • 4. L03A000101    From 59 To 82 E-value: 0.00003 Score: 38.9
        DTNFPICIFCCKCCNNSQCGICCK
  • 5. L12A06338|    From 59 To 82 E-value: 0.00005 Score: 38.1
        DTHFPICLFCCGCCNKSKCGICCK

Structure

  •   Domains
  •   1  Name:Hepcidin    Interpro Link:IPR010500
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Alizadeh M.,Pigeon C.,Troadec M.-B.,Courselaud B.,Ilyin G.,
  •   Title:Comparative analysis of mouse hepcidin 1 and 2 genes: evidence for different patterns of expression and co-inducibility during iron overload.
  •   Journal:FEBS Lett., 2003, 542, 22-26  [MEDLINE:22615571]
  •   [2]  Frith M.C.,Gough J.,Katayama S.,Kasukawa T.,Carninci P.,
  •   Title:The transcriptional landscape of the mammalian genome.
  •   Journal:Science, 2005, 309, 1559-1563  [PubMed:16141072]

Comments

  •   Comments

    •     No comments found on LAMP database



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