Record in detail


General Info

  • lamp_id:L01A003490
  • Name:DB125_HUMAN
  • FullName:Beta-defensin 125
  • Source:Homo sapiens
  • Mass:5730.6 Da
  • Sequence Length:47 aa
  • Isoelectric Point:9.17
  • Activity:Antibacterial
  • Sequence
        SFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISIISHEYTRR
  • Function:Has antibacterial activity (Potential).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003490    From 1 To 47 E-value: 5e-23 Score: 98.2
        SFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISIISHEYTRR
  • 2. L12A04323|    From 1 To 48 E-value: 0.000000000002 Score: 62.8
        GWEVKKCWKNNVGRCRQKCLHVERYKLLCMNKLSCCIPITSEEDYTPR
  • 3. L12A01523|    From 1 To 43 E-value: 0.000000000006 Score: 61.2
        ERCWKNNIGHCRKRCFHVERYKLLCMNKLTCCIPIKEDHGYTK
  • 4. L12A04401|    From 5 To 47 E-value: 0.000000000006 Score: 61.2
        ERCWKNNIGHCRKRCFHVERYKLLCMNKLTCCIPIKEDHGYTK
  • 5. L12A01522|    From 1 To 43 E-value: 0.000000000008 Score: 60.8
        ERCWKNNIGHCRKRCFHIERYKLLCMNKLSCCIPLTSDDPYTQ

Structure

  •   Domains

  •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Gilbert J.G.R.,Burton J.,Ashurst J.L.,Matthews L.H.,Deloukas P.,
  •   Title:The DNA sequence and comparative analysis of human chromosome 20.
  •   Journal:Nature, 2001, 414, 865-871  [MEDLINE:21638749]
  •   [2]  Jia H.P.,Walters J.D.,Bartlett J.A.,Mitros J.P.,Schutte B.C.,
  •   Title:Discovery of five conserved beta-defensin gene clusters using a computational search strategy.
  •   Journal:Proc. Natl. Acad. Sci. U.S.A., 2002, 99, 2129-2133  [MEDLINE:21843921]
  •   [3]  Conejo-Garcia J.-R.,Forssmann W.-G.,Schulz S.,Krause A.,Rodriguez-Jimenez F.-J.,
  •   Title:Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis.
  •   Journal:Genomics, 2003, 81, 175-183  [PubMed:12620395]
  •   [4]  
  •   Title:The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  •   Journal:Genome Res., 2004, 14, 2121-2127  [PubMed:15489334]

Comments

  •   Comments

  •     No comments found on LAMP database



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