Record in detail


General Info

  • lamp_id:L01A003513
  • Name:DB126_HUMAN
  • FullName:Beta-defensin 126
  • Source:Homo sapiens
  • Mass:4957.9 Da
  • Sequence Length:43 aa
  • Isoelectric Point:8.62
  • Activity:Antibacterial
  • Sequence
        NWYVKKCLNDVGICKKKCKPEEMHVKNGWAMCGKQRDCCVPAD
  • Function:Has antibacterial activity (Potential).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A12372|    From 1 To 43 E-value: 2e-22 Score: 96.3
        NWYVKKCLNDVGICKKKCKPEEMHVKNGWAMCGKQRDCCVPAD
  • 2. L01A003513    From 1 To 43 E-value: 1e-20 Score: 89.7
        NWYVKKCLNDVGICKKKCKPEEMHVKNGWAMCGKQRDCCVPAD
  • 3. L12A11346|    From 1 To 43 E-value: 2e-20 Score: 89.7
        SWYVKKCLNDVGICKKKCKPEELHVKNGWAMCGKQRDCCVPAD
  • 4. L12A09843|    From 1 To 43 E-value: 2e-20 Score: 89.7
        NWYVKKCLNDVGICKKKCKPEELHVKHGWAMCGKQRDCCVPAD
  • 5. L12A09847|    From 1 To 43 E-value: 3e-20 Score: 89
        NWYVKKCLNDVGICKKKCKPGEMHIKNGWATCGKQRDCCVPAD

Structure

  •   Domains
  •   1  Name:Beta_defensin_126    Interpro Link:IPR020329
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Hall L.,Coadwell W.J.,Moisyadi S.,Jones R.,Perry A.C.F.,
  •   Title:The novel epididymal secretory protein ESP13.2 in Macaca fascicularis.
  •   Journal:Biol. Reprod., 1999, 61, 965-972  [MEDLINE:99423524]
  •   [2]  Gilbert J.G.R.,Burton J.,Ashurst J.L.,Matthews L.H.,Deloukas P.,
  •   Title:The DNA sequence and comparative analysis of human chromosome 20.
  •   Journal:Nature, 2001, 414, 865-871  [MEDLINE:21638749]
  •   [3]  Jia H.P.,Walters J.D.,Bartlett J.A.,Mitros J.P.,Schutte B.C.,
  •   Title:Discovery of five conserved beta-defensin gene clusters using a computational search strategy.
  •   Journal:Proc. Natl. Acad. Sci. U.S.A., 2002, 99, 2129-2133  [MEDLINE:21843921]
  •   [4]  Conejo-Garcia J.-R.,Forssmann W.-G.,Schulz S.,Krause A.,Rodriguez-Jimenez F.-J.,
  •   Title:Distribution of new human beta-defensin genes clustered on chromosome 20 in functionally different segments of epididymis.
  •   Journal:Genomics, 2003, 81, 175-183  [PubMed:12620395]

Comments

  •   Comments

  •     No comments found on LAMP database



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