Record in detail


General Info

  • lamp_id:L01A003529
  • Name:GRAC_GRASX
  • FullName:Grammistin Gs C
  • Source:Grammistes sexlineatus
  • Mass:2758.3 Da
  • Sequence Length:26 aa
  • Isoelectric Point:11.13
  • Activity:Antibacterial
  • Sequence
        NWRKILGKIAKVAAGLLGSMLAGYQV
  • Function:Thanks to its amphiphilic alpha-helice(s), it may integrate into membrane phospholipids, leading to lysis of the membrane. Has no substantial hemolytic activity. Has antibacterial activity with a broad spectrum against various species of bacteria including both Gram-positive and Gram-negative groups.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003529    From 1 To 26 E-value: 0.000000003 Score: 52
        NWRKILGKIAKVAAGLLGSMLAGYQV
  • 2. L01A003467    From 1 To 25 E-value: 0.000001 Score: 43.5
        NWRKILGQIASVGAGLLGSLLAGYE
  • 3. L01A003530    From 2 To 25 E-value: 0.053 Score: 28.1
        WRELLKKLAFTAAGHLGSVLAAKQ
  • 4. L02A001466    From 2 To 14 E-value: 0.52 Score: 25
        NWKKILGKIIKVA
  • 5. L02A001465    From 2 To 14 E-value: 0.75 Score: 24.3
        NWKKVLGKIIKVA

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Shiomi K.,Nagashima Y.,Ishida M.,Araki M.,Sugiyama N.,
  •   Title:Further isolation and characterization of grammistins from the skin secretion of the soapfish Grammistes sexlineatus.
  •   Journal:Toxicon, 2005, 45, 595-601  [PubMed:15777955]

Comments

  •   Comments

    •     No comments found on LAMP database



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