Record in detail

lamp_id:L01A003552
Name:CECA_AEDAE
FullName:Cecropin-A
Source:Aedes aegypti
Mass:3391.1 Da
Sequence Length:34 aa
Isoelectric Point:11.18
Activity:Antibacterial, Antifungal
Sequence
GGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKAL
Function:Antibacterial activity against Gram-negative bacteria E.coli D22 and D31, E.carotovora, K.pneumoniae, P.aeruginosa, S.typhimurium, E.cloacae B12 and X.campestris and Gram-positive bacteria A.viridans, M.luteus, B.megaterium and S.pyogenes. Possesses antifungal activity against F.oxysporum, F.culmorum and N.crassa, C.albicans, C.neoformans and S.cerevisiae. No activity against Gram-negative S.marcescens Db11, Gram-positive B.cereus, B.subtilis, B.thuringiensis, S.aureus and L.monocytogenes, the fungi A.fumigatus and B.bassiana and C.glabrata.

Top similar AMPs on LAMP
1. L12A08760| From 24 To 57 E-value: 0.000000000002 Score: 63.2
GGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKAL
2. L03A000222 From 24 To 57 E-value: 0.000000000002 Score: 63.2
GGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKAL
3. L03A000219 From 24 To 57 E-value: 0.000000000002 Score: 63.2
GGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKAL
4. L03A000199 From 24 To 57 E-value: 0.000000000002 Score: 62.8
GGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKAL
5. L01A003552 From 1 To 34 E-value: 0.000000000004 Score: 62
GGLKKLGKKLEGAGKRVFNAAEKALPVVAGAKAL

Reference
[1] Richman A.,Kamal S.,Vizioli J.,Charlet M.,Lowenberger C.A.,
Title:Antimicrobial activity spectrum, cDNA cloning and mRNA expression of a newly isolated member of the cecropin family from the mosquito vector Aedes aegypti.
Journal:J. Biol. Chem., 1999, 274, 20092-20097 [MEDLINE:99329007]
[2] Kodira C.D.,Haas B.J.,Lawson D.,Wortman J.R.,Nene V.,
Title:Genome sequence of Aedes aegypti, a major arbovirus vector.
Journal:Science, 2007, 316, 1718-1723 [PubMed:17510324]