Record in detail


General Info

  • lamp_id:L01A003571
  • Name:DEF3_PAPHA
  • FullName:Defensin-3
  • Source:Papio hamadryas
  • Mass:3730.2 Da
  • Sequence Length:32 aa
  • Isoelectric Point:9.62
  • Activity:Antibacterial, Antifungal
  • Sequence
        RTCRCRLGRCSRRESYSGSCNINGRIYSLCCR
  • Function:Has antibacterial activity against the Gram-negative bacterium E.coli and the Gram-positive bacteria L.monocytogenes and S.aureus. Has antifungal activity against C.albicans.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003571    From 1 To 32 E-value: 0.000000000006 Score: 61.2
        RTCRCRLGRCSRRESYSGSCNINGRIYSLCCR
  • 2. L12A09204|    From 63 To 93 E-value: 0.00000002 Score: 49.7
        RTCHCR-SRCLRRESNSGSCNINGRIFSLCCR
  • 3. L12A09205|    From 63 To 93 E-value: 0.00000008 Score: 47.4
        RTCHCR-SRCLRRESNSGSCNINGRISSLCCR
  • 4. L12A09238|    From 63 To 93 E-value: 0.0000002 Score: 46.2
        RTCYCRIGRCFRRESSSGRCRISGRIYILCC
  • 5. L01A002694    From 2 To 32 E-value: 0.0000004 Score: 45.4
        RTCHCR-SRCLRRESNSGSCNINGRIFSLCCR

Structure

  •   Domains
  •   1  Name:Defensin_beta/neutrophil    Interpro Link:IPR006080
  •   2  Name:Mammalian_defensins    Interpro Link:IPR006081
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lehrer R.I.,Leonova L.E.,Shamova O.V.,Aleshina G.M.,Tsvetkova E.V.,
  •   Title:Alpha-defensins from blood leukocytes of the monkey Papio hamadryas.
  •   Journal:Biokhimiia, 2006, 71, 879-883  [PubMed:16978151]

Comments

  •   Comments

    •     No comments found on LAMP database



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