Record in detail
General Info
- lamp_id:L01A003618
- Name:GLL13_CHICK
- FullName:Gallinacin-13
- Source:Gallus gallus
- Mass:7450.3 Da
- Sequence Length:66 aa
- Isoelectric Point:8.65
- Activity:Antibacterial
- Sequence
FSDSQLCRNNHGHCRRLCFHMESWAGSCMNGRLRCCRFSTKQPFSNPKHSVLHTAEQDPSPSLGGT - Function:Has bactericidal activity. Potent activity against E.coli, L.monocytogenes, S.typhimurium and S.pyogenes but mot against S.aureus.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1114
- 2 Database:dbAMP dbAMP_02321
- 3 Database:DRAMP DRAMP03661
- 4 Database:Uniprot Q6IV18
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A09037| From 24 To 89 E-value: 4e-36 Score: 141
FSDSQLCRNNHGHCRRLCFHMESWAGSCMNGRLRCCRFSTKQPFSNPKHSVLHTAEQDPSPSLGGT - 2. L01A003618 From 1 To 66 E-value: 2e-35 Score: 139
FSDSQLCRNNHGHCRRLCFHMESWAGSCMNGRLRCCRFSTKQPFSNPKHSVLHTAEQDPSPSLGGT - 3. L13A023838 From 1 To 50 E-value: 2e-25 Score: 106
FSDSQLCRNNHGHCRRLCFHMESWAGSCMNGRLRCCRFSTKQPFSNPKHS - 4. L12A09038| From 25 To 61 E-value: 0.00000000000002 Score: 69.7
LSDSQQCRSNHGHCRRLCFHMERWEGSCSNGRLRCCR - 5. L12A11152| From 2 To 35 E-value: 0.000000000009 Score: 60.8
LSDTQQCRNNRGHCRRLCFHMERWEGSCSNGRLR
Structure
- Domains
- 1 Name:Defensin_beta-typ Interpro Link:IPR001855
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Cheng J.-F.,Matsuda Y.,Ando J.,Hughes A.L.,Xiao Y.,
- Title:A genome-wide screen identifies a single beta-defensin gene cluster in the chicken: implications for the origin and evolution of mammalian defensins.
- Journal:BMC Genomics, 2004, 5, 56-56 [PubMed:15310403]
- [2] Tierney J.,McMahon J.,Gaines S.,Lynn D.J.,Higgs R.,
- Title:The synthetic form of a novel chicken beta-defensin identified in silico is predominantly active against intestinal pathogens.
- Journal:Immunogenetics, 2005, 57, 90-98 [PubMed:15744537]
- [3] Yoshimura Y.,Nishibori M.,Isobe N.,Subedi K.,
- Title:Changes in the expression of gallinacins, antimicrobial peptides, in ovarian follicles during follicular growth and in response to lipopolysaccharide in laying hens (Gallus domesticus).
- Journal:Reproduction, 2007, 133, 127-133 [PubMed:17244739]
Comments
- Comments
No comments found on LAMP database