Record in detail


General Info

  • lamp_id:L01A003634
  • Name:WF15B_MOUSE
  • FullName:WAP four-disulfide core domain protein 15B
  • Source:Mus musculus
  • Mass:7134.4 Da
  • Sequence Length:60 aa
  • Isoelectric Point:8.77
  • Activity:Antibacterial
  • Sequence
        RPEIKKKNVFSKPGYCPEYRVPCPFVLIPKCRRDKGCKDALKCCFFYCQMRCVDPWESPE
  • Function:Antibacterial protein which inhibits the growth of E.coli and S.aureus.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A08041|    From 21 To 80 E-value: 5e-31 Score: 124
        RPEIKKKNVFSKPGYCPEYRVPCPFVLIPKCRRDKGCKDALKCCFFYCQMRCVDPWESPE
  • 2. L01A003634    From 1 To 60 E-value: 4e-30 Score: 121
        RPEIKKKNVFSKPGYCPEYRVPCPFVLIPKCRRDKGCKDALKCCFFYCQMRCVDPWESPE
  • 3. L13A016921    From 1 To 50 E-value: 6e-24 Score: 101
        RPEIKKKNVFSKPGYCPEYRVPCPFVLIPKCRRDKGCKDALKCCFFYCQM
  • 4. L01A003619    From 1 To 58 E-value: 2e-17 Score: 79.3
        QPRATRKGVTPKQGYCPEFLLDCPFVLLPVCSRDKGCKGTKKCCFYYCQMRCVEPWTT
  • 5. L01A003584    From 2 To 50 E-value: 0.00003 Score: 38.9
        KGNTEKPGVCPADNVRCIKSDPPQCHTDQDCQGIRKCCYLHCGFKCVIP

Structure

  •   Domains
  •   1  Name:4-disulphide_core    Interpro Link:IPR015874
  •   2  Name:Whey_acidic_protein_4-diS_core    Interpro Link:IPR008197
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Usui K.,Huqun X.,Endo Y.,Kikuchi T.,Hagiwara K.,
  •   Title:Mouse SWAM1 and SWAM2 are antibacterial proteins composed of a single whey acidic protein motif.
  •   Journal:J. Immunol., 2003, 170, 1973-1979  [MEDLINE:22462099]
  •   [2]  
  •   Title:The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
  •   Journal:Genome Res., 2004, 14, 2121-2127  [PubMed:15489334]
  •   [3]  Lundwall A.,Lilja H.,Clauss A.,
  •   Title:The evolution of a genetic locus encoding small serine proteinase inhibitors.
  •   Journal:Biochem. Biophys. Res. Commun., 2005, 333, 383-389  [PubMed:15950183]
  •   [4]  Frith M.C.,Gough J.,Katayama S.,Kasukawa T.,Carninci P.,
  •   Title:The transcriptional landscape of the mammalian genome.
  •   Journal:Science, 2005, 309, 1559-1563  [PubMed:16141072]
  •   [5]  Goldstein S.,Zody M.C.,Hillier L.W.,Goodstadt L.,Church D.M.,
  •   Title:Lineage-specific biology revealed by a finished genome assembly of the mouse.
  •   Journal:PLoS Biol., 2009, 7, 0-0  [PubMed:19468303]

Comments

  •   Comments

    •     No comments found on LAMP database



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