Record in detail
General Info
- lamp_id:L01A003635
- Name:WFD12_MOUSE
- FullName:WAP four-disulfide core domain protein 12
- Source:Mus musculus
- Mass:7287.1 Da
- Sequence Length:64 aa
- Isoelectric Point:4.31
- Activity:Antibacterial
- Sequence
GGVKGEEKRVCPPDYVRCIRQDDPQCYSDNDCGDQEICCFWQCGFKCVLPVKDNSEEQIPQSKV - Function:Antibacterial protein which inhibits the growth of E.coli and S.aureus. Putative acid-stable proteinase inhibitor.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ1123
- 2 Database:DBAASP 2140
- 3 Database:dbAMP dbAMP_02769
- 4 Database:DRAMP DRAMP03400
- 5 Database:Uniprot Q9JHY3
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A09623| From 22 To 85 E-value: 1e-33 Score: 133
GGVKGEEKRVCPPDYVRCIRQDDPQCYSDNDCGDQEICCFWQCGFKCVLPVKDNSEEQIPQSKV - 2. L01A003635 From 1 To 64 E-value: 1e-32 Score: 129
GGVKGEEKRVCPPDYVRCIRQDDPQCYSDNDCGDQEICCFWQCGFKCVLPVKDNSEEQIPQSKV - 3. L13A022919 From 1 To 50 E-value: 6e-25 Score: 104
GGVKGEEKRVCPPDYVRCIRQDDPQCYSDNDCGDQEICCFWQCGFKCVLP - 4. L01A003630 From 1 To 57 E-value: 2e-20 Score: 89.7
GGVKGAEKGVCPPDNVRCIRGEDPQCHNDNDCKDQKICCYWHCGFKCVQPVKDSWEQ - 5. L01A003594 From 1 To 56 E-value: 0.000000000007 Score: 61.2
VKGNIEKPEVCPADNVRCIKSDPPQCHTDQDCQGIRKCCYLHCGFKCVIPVKELEE
Structure
- Domains
- 1 Name:Whey_acidic_protein_4-diS_core Interpro Link:IPR008197
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Usui K.,Huqun X.,Endo Y.,Kikuchi T.,Hagiwara K.,
- Title:Mouse SWAM1 and SWAM2 are antibacterial proteins composed of a single whey acidic protein motif.
- Journal:J. Immunol., 2003, 170, 1973-1979 [MEDLINE:22462099]
- [2]
- Title:The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
- Journal:Genome Res., 2004, 14, 2121-2127 [PubMed:15489334]
Comments
- Comments
No comments found on LAMP database