Record in detail


General Info

  • lamp_id:L01A003712
  • Name:DB124_HUMAN
  • FullName:Beta-defensin 124
  • Source:Homo sapiens
  • Mass:5711.5 Da
  • Sequence Length:49 aa
  • Isoelectric Point:7.78
  • Activity:Antibacterial
  • Sequence
        EFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKPPPVPKHEYE
  • Function:Has antibacterial activity (Potential).

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L01A003712    From 1 To 49 E-value: 5e-25 Score: 104
        EFKRCWKGQGACQTYCTRQETYMHLCPDASLCCLSYALKPPPVPKHEYE
  • 2. L12A04032|    From 4 To 52 E-value: 1e-24 Score: 103
        EFKRCWKGQGACRTYCTRQETYMHLCPDASLCCLSYALKPPPVPKHEYE
  • 3. L01A003700    From 1 To 49 E-value: 2e-24 Score: 103
        EFKRCWKGQGACRTYCTRQETYMHLCPDASLCCLSYALKPPPVPKHEYE
  • 4. L12A01350|    From 1 To 49 E-value: 2e-23 Score: 99
        EFKRCWKGQGACRTYCTRQETYMHLCPDASLCCLSYALKPPPVPKSKYE
  • 5. L12A01349|    From 1 To 49 E-value: 2e-23 Score: 99
        EFKRCWKGQGACRTYCTRQETYMHLCPDASLCCLSYALKPPPVPKNGYE

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Gilbert J.G.R.,Burton J.,Ashurst J.L.,Matthews L.H.,Deloukas P.,
  •   Title:The DNA sequence and comparative analysis of human chromosome 20.
  •   Journal:Nature, 2001, 414, 865-871  [MEDLINE:21638749]
  •   [2]  Jia H.P.,Walters J.D.,Bartlett J.A.,Mitros J.P.,Schutte B.C.,
  •   Title:Discovery of five conserved beta-defensin gene clusters using a computational search strategy.
  •   Journal:Proc. Natl. Acad. Sci. U.S.A., 2002, 99, 2129-2133  [MEDLINE:21843921]
  •   [3]  Zhang G.,Blecha F.,Sang Y.,Cai Y.,Patil A.A.,
  •   Title:Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
  •   Journal:Physiol. Genomics, 2005, 23, 5-17  [PubMed:16033865]

Comments

  •   Comments

    •     No comments found on LAMP database



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