Record in detail

lamp_id:L01A003734
Name:OXLA_PROMU
FullName:L-amino-acid oxidase
Source:Protobothrops mucrosquamatus
Mass:2931.1 Da
Sequence Length:24 aa
Isoelectric Point:4.02
Activity:Antibacterial
Sequence
ADNKNPLEECFRETNYEEFLEIAR
Function:Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme. Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis, and antiparasitic activities (By similarity). This protein has antibacterial activity (against E.coli, S.aureus, and B.dysenteriae), cytotoxic activity, as well as an ability to induce platelet aggregation. Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation. These different effects are probably due to different experimental conditions.

Top similar AMPs on LAMP
1. L01A003734 From 1 To 24 E-value: 0.000000009 Score: 50.4
ADNKNPLEECFRETNYEEFLEIAR
2. L01A003738 From 1 To 24 E-value: 0.00000004 Score: 48.5
ADDRNPLEQCFRETDYEEFLEIAR
3. L13A010532 From 1 To 24 E-value: 0.00000008 Score: 47.4
ADDRNPLEQCFRETDYEEFLEIAR
4. L01A003737 From 1 To 24 E-value: 0.00001 Score: 40.4
ADDKNPLEEAFREADYEVFLEIAK
5. L01A003739 From 1 To 23 E-value: 0.00002 Score: 39.7
ADDKNPLEE-FRETNYEVFLEIAK

Reference
[1] Jin Y.,Tai H.,Lu Q.-M.,Wei Q.,Wei J.-F.,
Title:Purification, characterization and biological activity of an L-amino acid oxidase from Trimeresurus mucrosquamatus venom.
Journal:Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao, 2003, 35, 219-224 [PubMed:12621545]