Record in detail

lamp_id:L01A003737
Name:OXLA_ERIMA
FullName:L-amino-acid oxidase
Source:Eristicophis macmahoni
Mass:3097.3 Da
Sequence Length:27 aa
Isoelectric Point:3.88
Activity:Antibacterial
Sequence
ADDKNPLEEAFREADYEVFLEIAKNGL
Function:Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme. Exhibits diverse biological activities, such as hemolysis, edema, apoptosis, as well as induction of platelet aggregation. Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation. These different effects are probably due to different experimental conditions. Unlike other snake venom L-amino acid oxidases, does not induce hemorrhage. This protein may also have antibacterial and antiparasitic activities.

Top similar AMPs on LAMP
1. L01A003737 From 1 To 27 E-value: 0.0000000003 Score: 55.5
ADDKNPLEEAFREADYEVFLEIAKNGL
2. L01A003739 From 1 To 26 E-value: 0.00000006 Score: 47.8
ADDKNPLEE-FRETNYEVFLEIAKNGL
3. L01A003738 From 1 To 27 E-value: 0.0000002 Score: 46.2
ADDRNPLEQCFRETDYEEFLEIARNNL
4. L13A010532 From 1 To 27 E-value: 0.0000003 Score: 45.8
ADDRNPLEQCFRETDYEEFLEIARNNL
5. L01A003736 From 2 To 27 E-value: 0.00001 Score: 40.4
DRRSPLEECFQQNDYEEFLEIAKNGL

Reference
[1] Kayed R.,Alam J.M.,Abbasi A.,Stoeva S.,Ali S.A.,
Title:Isolation, structural, and functional characterization of an apoptosis-inducing L-amino acid oxidase from leaf-nosed viper (Eristocophis macmahoni) snake venom.
Journal:Arch. Biochem. Biophys., 2000, 384, 216-226 [PubMed:11368308]