Record in detail

lamp_id:L01A003738
Name:OXLA_CRODC
FullName:L-amino-acid oxidase
Source:Crotalus durissus cascavella
Mass:6561.3 Da
Sequence Length:61 aa
Isoelectric Point:4.88
Activity:Antibacterial, Antiparasitic
Sequence
ADDRNPLEQCFRETDYEEFLEIARNNLKATSNPKHVVIVGAGMAGLSAAYVLSGGGHQVTV
Function:Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme. Exhibits diverse biological activities, such as apoptosis, antibacterial activities against both Gram-negative and Gram-positive bacteria and antiparasitic activities, as well as induction of platelet aggregation. Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation. These different effects are probably due to different experimental conditions. This protein may also induce hemorrhage, hemolysis, and edema.

Top similar AMPs on LAMP
1. L01A003738 From 1 To 61 E-value: 2e-32 Score: 129
ADDRNPLEQCFRETDYEEFLEIARNNLKATSNPKHVVIVGAGMAGLSAAYVLSGGGHQVTV
2. L13A010532 From 1 To 50 E-value: 9e-26 Score: 107
ADDRNPLEQCFRETDYEEFLEIARNNLKATSNPKHVVIVGAGMAGLSAAY
3. L01A003739 From 1 To 49 E-value: 4e-19 Score: 85.1
ADDKNPLEE-FRETNYEVFLEIAKNGLKATSNPKRVVIVGAGMAGLSAAY
4. L01A003736 From 2 To 38 E-value: 0.00000000001 Score: 60.1
DRRSPLEECFQQNDYEEFLEIAKNGLKKTXNPKHVXV
5. L01A003734 From 1 To 24 E-value: 0.00000005 Score: 48.5
ADNKNPLEECFRETNYEEFLEIAR

Reference
[1] Corbett C.E.,Laurenti M.D.,Passero L.F.,Toyama Dde O.,Toyama M.H.,
Title:Isolation of a new L-amino acid oxidase from Crotalus durissus cascavella venom.
Journal:Toxicon, 2006, 47, 47-57 [PubMed:16307769]