Record in detail
General Info
- lamp_id:L01A003741
- Name:OXLA_BITGA
- FullName:L-amino-acid oxidase
- Source:Bitis gabonica
- Mass:7322.6 Da
- Sequence Length:60 aa
- Isoelectric Point:10.51
- Activity:Antibacterial
- Sequence
GPMRIPEKHRIVREYIRKFGLQLNEFVQETENAWYYIKNIRKKVHEVKKDPGLLKYPVKP - Function:Catalyzes an oxidative deamination of predominantly hydrophobic and aromatic L-amino acids, thus producing hydrogen peroxide that may contribute to the diverse toxic effects of this enzyme. Exhibits diverse biological activities, such as hemorrhage, hemolysis, edema, apoptosis of vascular endothelial cells or tumor cell lines, antibacterial and antiparasitic activities, as well as regulation of platelet aggregation. Effects of snake L-amino oxidases on platelets are controversial, since they either induce aggregation or inhibit agonist-induced aggregation. These different effects are probably due to different experimental conditions (By similarity).
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ2124
- 2 Database:dbAMP dbAMP_03928
- 3 Database:DRAMP DRAMP02464
- 4 Database:Uniprot Q6T627
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L01A003741 From 1 To 60 E-value: 2e-30 Score: 122
GPMRIPEKHRIVREYIRKFGLQLNEFVQETENAWYYIKNIRKKVHEVKKDPGLLKYPVKP - 2. L01A000174 From 1 To 22 E-value: 9.3 Score: 20.8
ETESTPDYLKNIQQQLEEYTKN - 3. L13A013420 From 1 To 22 E-value: 9.6 Score: 20.8
ETESTPDYLKNIQQQLEEYTKN
Structure
- Domains
No domains found on LAMP database
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Ribeiro J.M.C.,Garfield M.K.,Harrison J.,My-Pham V.,Francischetti I.M.B.,
- Title:Bitis gabonica (Gaboon viper) snake venom gland: toward a catalog for the full-length transcripts (cDNA) and proteins.
- Journal:Gene, 2004, 337, 55-69 [PubMed:15276202]
Comments
- Comments
No comments found on LAMP database