Record in detail


General Info

  • lamp_id:L01A003856
  • Name:LAN15_STAEP
  • FullName:Lantibiotic epilancin 15X
  • Source:Staphylococcus epidermidis
  • Mass:3316 Da
  • Sequence Length:31 aa
  • Isoelectric Point:10.8
  • Activity:Antibacterial
  • Sequence
        SASIVKTTIKASKKLCRGFTLTCGCHFTGKK
  • Function:Lanthionine-containing peptide antibiotic (lantibiotic) active on Gram-positive bacteria such as staphylococci, enterococci and streptococci. The bactericidal activity of lantibiotics is based on depolarization of energized bacterial cytoplasmic membranes, initiated by the formation of aqueous transmembrane pores.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A07943|    From 25 To 55 E-value: 0.000000000001 Score: 63.5
        SASIVKTTIKASKKLCRGFTLTCGCHFTGKK
  • 2. L01A003856    From 1 To 31 E-value: 0.000000000005 Score: 61.2
        SASIVKTTIKASKKLCRGFTLTCGCHFTGKK
  • 3. L02A001612    From 1 To 30 E-value: 0.00000000002 Score: 59.7
        ASIVKTTIKASKKLCRGFTLTCGCHFTGKK
  • 4. L12A12132|    From 2 To 31 E-value: 0.00000000003 Score: 58.9
        ASIVKTTIKAAKKLCRGFTLTCGCHFTGKK
  • 5. L13A022366    From 1 To 30 E-value: 0.00000000005 Score: 58.2
        AUIVKTTIKASKKLCRGFTLTCGCHFTGKK

Structure

  •   Domains

    •     No domains found on LAMP database
  •   Structures

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Milatovic D.,de Jong A.,Danny Hsu S.-T.,Hanssen M.,Ekkelenkamp M.B.,
  •   Title:Isolation and structural characterization of epilancin 15X, a novel lantibiotic from a clinical strain of Staphylococcus epidermidis.
  •   Journal:FEBS Lett., 2005, 579, 1917-1922  [PubMed:15792796]

Comments

  •   Comments

    •     No comments found on LAMP database



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