Record in detail
General Info
- lamp_id:L01A003858
- Name:DEF_GLOMM
- FullName:Defensin-A
- Source:Glossina morsitans morsitans
- Mass:4784.5 Da
- Sequence Length:43 aa
- Isoelectric Point:8.86
- Activity:Antibacterial
- Sequence
VTGELKRDKRVTCNIGEWVCVAHCNSKSKKSGYCSRGVCYCTN - Function:Antibacterial peptide mostly active against Gram-positive and Gram negative bacteria.
Cross-Linking
- Cross-linking
- 1 Database:CAMP CAMPSQ2208
- 2 Database:dbAMP dbAMP_11942
- 3 Database:DRAMP DRAMP03062
- 4 Database:SATPdb satpdb16898
- 5 Database:Uniprot Q8WTD4
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A07900| From 45 To 87 E-value: 3e-21 Score: 92
VTGELKRDKRVTCNIGEWVCVAHCNSKSKKSGYCSRGVCYCTN - 2. L01A003858 From 1 To 43 E-value: 4e-20 Score: 88.2
VTGELKRDKRVTCNIGEWVCVAHCNSKSKKSGYCSRGVCYCTN - 3. L02A001367 From 1 To 33 E-value: 0.00000000000004 Score: 68.6
VTCNIGEWVCVAHCNSKSKKSGYCSRGVCYCTN - 4. L12A07870| From 47 To 88 E-value: 0.0002 Score: 36.2
AELNRHKRLTCEIDRSLCLLHCRLKGYLRAYCSQQKVCRCVQ - 5. L03A000168 From 55 To 98 E-value: 0.002 Score: 33.1
RLKRATCDLLSGFGVGDSACAAHCIARGNRGGYCNSKKVCVCRN
Structure
- Domains
- 1 Name:Defensin_invertebrate/fungal Interpro Link:IPR001542
- Structures
No structs found on LAMP database
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Kwon J.,Gibson W.C.,Lehane M.J.,Kasumba I.,Hao Z.,
- Title:Tsetse immune responses and trypanosome transmission: implications for the development of tsetse-based strategies to reduce trypanosomiasis.
- Journal:Proc. Natl. Acad. Sci. U.S.A., 2001, 98, 12648-12653 [MEDLINE:21532909]
- [2] Bulet P.,Kunz C.,Ehret-Sabatier L.,Brun R.,Boulanger N.,
- Title:Immunopeptides in the defense reactions of Glossina morsitans to bacterial and Trypanosoma brucei brucei infections.
- Journal:Insect Biochem. Mol. Biol., 2002, 32, 369-375 [MEDLINE:21883850]
Comments
- Comments
No comments found on LAMP database