Record in detail


General Info

  • lamp_id:L02A000010
  • Name:CTHL3_BOVIN
  • FullName:Cathelicidin-3
  • Source:Bos taurus
  • Mass:7023.5 Da
  • Sequence Length:60 aa
  • Isoelectric Point:13.7
  • Activity:Antibacterial,Antifungal,Antiviral,
  • Sequence
        RRIRPRPPRLPRPRPRPLPFPRPGPRPIPRPLPFPRPGPRPIPRPLPFPRPGPRPIPRPL
  • Function:Exerts, in vitro, a potent antimicrobial activity. Probably due to an impairment of the function of the respiratory chain and of energy-dependent activities in the inner membrane of susceptible microorganisms.

Cross-Linking

  •   Cross-linking
  •   1  Database:APD  10
  •   2  Database:CAMP  CAMPSQ2704
  •   3  Database:DBAASP  5242
  •   4  Database:dbAMP  dbAMP_10671
  •   5  Database:DRAMP  DRAMP18707
  •   6  Database:Uniprot  P19661

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L02A000010    From 1 To 60 E-value: 7e-19 Score: 84.3
        RRIRPRPPRLPRPRPRPLPFPRPGPRPIPRPLPFPRPGPRPIPRPLPFPRPGPRPIPRPL
  • 2. L12A09995|    From 1 To 14 E-value: 0.43 Score: 25
        PRPLPFPRPGPRPI
  • 3. L12A09995|    From 1 To 14 E-value: 0.43 Score: 25
        PRPLPFPRPGPRPI
  • 4. L12A09995|    From 1 To 14 E-value: 0.43 Score: 25
        PRPLPFPRPGPRPI

Structure

  •   Domains
  •   1  Name:Cathelicidin    Interpro Link:IPR001894
  •   2  Name:Cathelicidin_CS    Interpro Link:IPR018216
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Romeo D.,Przybylski M.,Schneider K.,Gennaro R.,Frank R.W.,
  •   Title:Amino acid sequences of two proline-rich bactenecins. Antimicrobial peptides of bovine neutrophils.
  •   Journal:J. Biol. Chem., 1990, 265, 18871-18874  [MEDLINE:91035404]
  •   [2]  Zanetti M.,Romeo D.,Scocchi M.,
  •   Title:Molecular cloning of Bac7, a proline- and arginine-rich antimicrobial peptide from bovine neutrophils.
  •   Journal:FEBS Lett., 1994, 352, 197-200  [MEDLINE:95010707]
  •   [3]  Romeo D.,Lenarcic B.,Tossi A.,Storici P.,
  •   Title:Purification and structural characterization of bovine cathelicidins, precursors of antimicrobial peptides.
  •   Journal:Eur. J. Biochem., 1996, 238, 769-776  [MEDLINE:96300243]

Comments

  •   Comments

    •     No comments found on LAMP database



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