Record in detail

General Info

lamp_id:L02A000017
Name:AUR24_LITAU
FullName:Aurein-2.4
Source:Litoria aurea
Mass:1630 Da
Sequence Length:16 aa
Isoelectric Point:9.53
Activity:Antibacterial,Antifungal,Antiviral,,Anticancer
Sequence
GLFDIVKKVVGTLAGL
Function:Antimicrobial activity against B.cereus, L.lactis, L.innocua, M.luteus, S.aureus, S.epidermidis and S.uberis. Probably acts by disturbing membrane functions with its amphipathic structure. Shows anticancer activity.

Cross-Linking

Cross-linking
1 Database:APD 17
2 Database:CAMP CAMPSQ2706
3 Database:dbAMP dbAMP_03296
4 Database:DRAMP DRAMP01611
5 Database:SATPdb satpdb11579
6 Database:Uniprot P82391

Top similar AMPs

Top similar AMPs on LAMP
1. L02A000017 From 1 To 16 E-value: 0.003 Score: 32
GLFDIVKKVVGTLAGL
2. L13A028615 From 1 To 16 E-value: 0.005 Score: 30.8
GLFDIVKKVVGTIAGL
3. L13A011030 From 1 To 16 E-value: 0.005 Score: 30.8
GLFDIVKKVVGTIAGL
4. L13A012917 From 1 To 15 E-value: 0.007 Score: 30.4
GLFDIVKKVVGTLAG
5. L12A06194| From 50 To 65 E-value: 0.032 Score: 28.1
GLFDIVKKVVGAIGSL

Structure

Domains
1 Name:Aurein_antimicrobial_peptide Interpro Link:IPR013157

Structures

Activity

Antibacterial Activities

Toxicity

Toxicity

Reference

Reference
[1] Carver J.A.,Olver I.N.,Bowie J.H.,Wegener K.L.,Rozek T.,
Title:The antibiotic and anticancer active aurein peptides from the australian bell frogs Litoria aurea and Litoria raniformis the solution structure of aurein 1.2.
Journal:Eur. J. Biochem., 2000, 267, 5330-5341 [MEDLINE:20408845]

Comments

Comments