Record in detail


General Info

  • lamp_id:L02A000038
  • Name:DEFB3_BOVIN
  • FullName:Beta-defensin 3
  • Source:Bos taurus
  • Mass:4833.7 Da
  • Sequence Length:42 aa
  • Isoelectric Point:11.71
  • Activity:Antibacterial,Antifungal,Antiviral,
  • Sequence
        QGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
  • Function:Has bactericidal activity. Active against E.coli ML35 and S.aureus 502A.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000069    From 16 To 57 E-value: 6e-20 Score: 87.8
        QGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
  • 2. L12A02363|    From 3 To 44 E-value: 3e-19 Score: 85.5
        QGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
  • 3. L12A09073|    From 23 To 64 E-value: 3e-19 Score: 85.5
        QGARNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
  • 4. L02A000038    From 1 To 42 E-value: 3e-19 Score: 85.5
        QGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
  • 5. L01A000363    From 1 To 42 E-value: 6e-19 Score: 84.3
        EGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW

Structure

  •   Domains
  •   1  Name:Defensin_beta-typ    Interpro Link:IPR001855
  •   2  Name:Defensin_beta/neutrophil    Interpro Link:IPR006080
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Novotny M.J.,McGuire P.A.,Morris W.L.,Tang Y.-Q.,Selsted M.E.,
  •   Title:Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
  •   Journal:J. Biol. Chem., 1993, 268, 6641-6648  [MEDLINE:93203264]
  •   [2]  Erdjument-Bromage H.,Russell J.P.,Diamond G.,Clark D.P.,Tarver A.P.,
  •   Title:Enteric beta-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection.
  •   Journal:Infect. Immun., 1998, 66, 1045-1056  [MEDLINE:98147718]

Comments

  •   Comments

  •     No comments found on LAMP database



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