Record in detail


General Info

  • lamp_id:L02A000045
  • Name:DFB10_BOVIN
  • FullName:Beta-defensin 10
  • Source:Bos taurus
  • Mass:4526.4 Da
  • Sequence Length:40 aa
  • Isoelectric Point:10.46
  • Activity:Antibacterial,Antifungal,Antiviral,
  • Sequence
        QGVRSYLSCWGNRGICLLNRCPGRMRQIGTCLAPRVKCCR
  • Function:Has bactericidal activity. Active against E.coli ML35 and S.aureus 502A.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L12A09087|    From 23 To 62 E-value: 9e-19 Score: 84
        QGVRSYLSCWGNRGICLLNRCPGRMRQIGTCLAPRVKCCR
  • 2. L12A09092|    From 23 To 62 E-value: 1e-18 Score: 83.6
        QGVRSYLSCWGNRGICLLNRCPGRMRQIGTCLAPRVKCCR
  • 3. L12A02365|    From 3 To 42 E-value: 3e-18 Score: 82
        QGVRSYLSCWGNRGICLLNRCPGRMRQIGTCLAPRVKCCR
  • 4. L02A000045    From 1 To 40 E-value: 5e-18 Score: 81.6
        QGVRSYLSCWGNRGICLLNRCPGRMRQIGTCLAPRVKCCR
  • 5. L01A000369    From 1 To 40 E-value: 8e-18 Score: 80.9
        EGVRSYLSCWGNRGICLLNRCPGRMRQIGTCLAPRVKCCR

Structure

  •   Domains
  •   1  Name:Defensin_beta-typ    Interpro Link:IPR001855
  •   2  Name:Defensin_beta/neutrophil    Interpro Link:IPR006080
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Novotny M.J.,McGuire P.A.,Morris W.L.,Tang Y.-Q.,Selsted M.E.,
  •   Title:Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
  •   Journal:J. Biol. Chem., 1993, 268, 6641-6648  [MEDLINE:93203264]
  •   [2]  Kalm E.,Schroder J.M.,Paul S.,Exner K.,Roosen S.,
  •   Title:Bovine beta-defensins: identification and characterization of novel bovine beta-defensin genes and their expression in mammary gland tissue.
  •   Journal:Mamm. Genome, 2004, 15, 834-842  [PubMed:15520886]

Comments

  •   Comments

  •     No comments found on LAMP database



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