Record in detail
General Info
- lamp_id:L02A000121
- Name:RN2P_RANPI
- FullName:Ranatuerin-2P
- Source:Rana pipiens
- Mass:3002.6 Da
- Sequence Length:28 aa
- Isoelectric Point:9.55
- Activity:Antibacterial,Antifungal,Antiviral,
- Sequence
GLMDTVKNVAKNLAGHMLDKLKCKITGC - Function:Antibacterial activity against Gram-positive bacterium S.aureus and Gram-negative bacterium E.coli. Has activity against C.albicans.
Cross-Linking
- Cross-linking
- 1 Database:APD 121
- 2 Database:dbAMP dbAMP_03677
- 3 Database:SATPdb satpdb19439
- 4 Database:Uniprot P82847
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A07248| From 44 To 71 E-value: 0.00000000002 Score: 59.3
GLMDTVKNVAKNLAGHMLDKLKCKITGC - 2. L12A10422| From 19 To 46 E-value: 0.00000000004 Score: 58.9
GLMDTVKNVAKNLAGHMLDKLKCKITGC - 3. L02A000121 From 1 To 28 E-value: 0.00000000009 Score: 57.4
GLMDTVKNVAKNLAGHMLDKLKCKITGC - 4. L12A01004| From 14 To 40 E-value: 0.0000000003 Score: 55.5
GLMDTVKNVAKNLAGHMLDKLKCKITG - 5. L01A000358 From 1 To 27 E-value: 0.0000000003 Score: 55.5
LMDTVKNVAKNLAGHMLDKLKCKITGC
Activity
- Antibacterial Activities
- 1 Target: E. coli MIC: 39.0338 μg/ml (13 μM)
- 2 Target: S. aureus MIC: 150.13 μg/ml (50 μM)
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Knoop F.C.,O"Flaherty M.,Li Z.,Wang Y.,Goraya J.,
- Title:Peptides with antimicrobial activity from four different families isolated from the skins of the North American frogs Rana luteiventris, Rana berlandieri and Rana pipiens.
- Journal:Eur. J. Biochem., 2000, 267, 894-900 [MEDLINE:20117700]
- [2] Rao P.,Orr D.F.,Bjourson A.J.,Farragher S.M.,Chen T.,
- Title:Granular gland transcriptomes in stimulated amphibian skin secretions.
- Journal:Biochem. J., 2003, 371, 125-130 [PubMed:12413397]
Comments
- Comments
No comments found on LAMP database