Record in detail


General Info

  • lamp_id:L02A000200
  • Name:CICH_TORMA
  • FullName:Chloride channel protein
  • Source:Torpedo marmorata
  • Mass:1613 Da
  • Sequence Length:14 aa
  • Isoelectric Point:11.28
  • Activity:Antibacterial,Antifungal,Antiviral,,Anticancer
  • Sequence
        LKLKSIVSWAKKVL
  • Function:Voltage-gated chloride channel. This channel is thought to ensure the high conductance of the non-innervated membrane of the electrocyte necessary for efficient current generation caused by sodium influx through the acetylcholine receptor at the innervated membrane.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L02A000200    From 1 To 14 E-value: 0.071 Score: 26.9
        LKLKSIVSWAKKVL
  • 2. L11A012793    From 1 To 14 E-value: 0.14 Score: 25.8
        LKLKNIVSWAKKVL
  • 3. L11A012794    From 1 To 14 E-value: 0.18 Score: 25.4
        LKLKSIVSYAKKVL
  • 4. L13A011599    From 1 To 13 E-value: 0.19 Score: 25.4
        LKLKSIVSWAKKV
  • 5. L13A017711    From 1 To 14 E-value: 0.23 Score: 25.4
        LKLKSIVSWAKAVL

Structure

  •   Domains
  •   1  Name:Cl-channel_core    Interpro Link:IPR014743
  •   2  Name:Cl-channel_volt-gated    Interpro Link:IPR001807
  •   3  Name:Cl_channel-0    Interpro Link:IPR002242
  •   4  Name:Cysta_beta_synth_core    Interpro Link:IPR000644
  •   Structures
  •   1
    PDB:2D4Z

    Method:X-ray
    Chains:A/B=525-774

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Schwarz G.,Steinmeyer K.,Jentsch T.J.,
  •   Title:Primary structure of Torpedo marmorata chloride channel isolated by expression cloning in Xenopus oocytes.
  •   Journal:Nature, 1990, 348, 510-514  [MEDLINE:91061906]
  •   [2]  Dutzler R.,Meyer S.,
  •   Title:Crystal structure of the cytoplasmic domain of the chloride channel ClC-0.
  •   Journal:Structure, 2006, 14, 299-307  [PubMed:16472749]

Comments

  •   Comments

  •     No comments found on LAMP database



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