Record in detail


General Info

  • lamp_id:L02A000400
  • Name:SPYY_PHYBI
  • FullName:Skin peptide tyrosine-tyrosine
  • Source:Phyllomedusa bicolor
  • Mass:4264.7 Da
  • Sequence Length:36 aa
  • Isoelectric Point:7.53
  • Activity:Antibacterial,Antifungal,Antiviral,,,Insecticidal
  • Sequence
        YPPKPESPGEDASPEEMNKYLTALRHYINLVTRQRY
  • Function:Shows a broad spectrum of antibacterial activity against Gram-positive and Gram-negative bacteria, yeast and fungi.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L02A000400    From 1 To 36 E-value: 2e-16 Score: 76.3
        YPPKPESPGEDASPEEMNKYLTALRHYINLVTRQRY
  • 2. L11A004190    From 1 To 36 E-value: 0.00000000001 Score: 60.5
        YPIKPEAPREDASPEELNRYYASLRHYLNLVTRQRY
  • 3. L02A001474    From 1 To 36 E-value: 0.00000000007 Score: 57.8
        YPSKPDNPGEDAPAEDMARYYSALRHYINLITRQRY
  • 4. L13A020613    From 1 To 36 E-value: 0.0000000002 Score: 56.6
        YPSKPDNPGEDAPAEDLARYYSALRHYINLITRQRY
  • 5. L01A000303    From 1 To 23 E-value: 0.00000001 Score: 50.4
        PEEMNKYLTALRHYINLVTRQRY

Structure

  •   Domains
  •   1  Name:Pancreatic_hormone-like    Interpro Link:IPR001955
  •   2  Name:Pancreatic_hormone-like_CS    Interpro Link:IPR020392
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Nicolas P.,Vaudry H.,Chartrel N.,Mor A.,
  •   Title:Skin peptide tyrosine-tyrosine, a member of the pancreatic polypeptide family: isolation, structure, synthesis, and endocrine activity.
  •   Journal:Proc. Natl. Acad. Sci. U.S.A., 1994, 91, 10295-10299  [MEDLINE:95024100]
  •   [2]  Mor A.,Nicolas P.,Shai Y.,Vouldoukis I.,
  •   Title:Broad spectrum antibiotic activity of the skin-PYY.
  •   Journal:FEBS Lett., 1996, 380, 237-240  [MEDLINE:96186932]

Comments

  •   Comments

  •     No comments found on LAMP database



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