Record in detail


General Info

  • lamp_id:L03A000002
  • Name:PF12_PIG
  • FullName:Prophenin-2
  • Source:Sus scrofa
  • Mass:9050.5 Da
  • Sequence Length:82 aa
  • Isoelectric Point:13.35
  • Activity:Antimicrobial
  • Sequence
        AFPPPNFPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPPFPPPIFPGPWFPPPPPFRPPPFGPPRFPGRR
  • Function:Exerts antimicrobial activity. It is more effective against Gram-negative bacteria than Gram-positive bacteria.

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  P51525
  •   2  Database:AMD  PF_PIG

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000002    From 1 To 82 E-value: 1e-28 Score: 116
        AFPPPNFPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPPFPPPIFPGPWFPPPPPFRPPPFGPPRFPGRR
  • 2. L13A013494    From 1 To 50 E-value: 0.000000000000002 Score: 72.8
        AFPPPNVPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGP
  • 3. L13A013494    From 1 To 50 E-value: 0.0000000000004 Score: 65.1
        AFPPPNVPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGP
  • 4. L13A013494    From 1 To 45 E-value: 0.000000001 Score: 53.5
        AFPPPNVPGPRFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPP
  • 5. L13A018643    From 1 To 50 E-value: 0.00000000000001 Score: 70.1
        AFPPPNVPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGPRFPPPNFPGP

Structure

  •   Domains
  •   1  Name:Cathelicidin    Interpro Link:IPR001894
  •   2  Name:Cathelicidin_CS    Interpro Link:IPR018216
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Lenarcic B.,Renko M.,Kopitar G.,Strukelj B.,Pungercar J.,
  •   Title:Molecular cloning of a putative homolog of proline/arginine-rich antibacterial peptides from porcine bone marrow.
  •   Journal:FEBS Lett., 1993, 336, 284-288  [MEDLINE:94085623]
  •   [2]  Lehrer R.I.,Ganz T.,Zhao C.,
  •   Title:Structures of genes for two cathelin-associated antimicrobial peptides: prophenin-2 and PR-39.
  •   Journal:FEBS Lett., 1995, 376, 130-134  [MEDLINE:96105365]

Comments

  •   Comments

  •     No comments found on LAMP database



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