Record in detail
General Info
- lamp_id:L03A000031
- Name:DEFI_MYTGA
- FullName:Defensin MGD-1
- Source:Mytilus galloprovincialis
- Mass:4408 Da
- Sequence Length:39 aa
- Isoelectric Point:8.78
- Activity:Antimicrobial
- Sequence
GFGCPNNYQCHRHCKSIPGRCGGYCGGWHRLRCTCYRCG - Function:Active against both Gram-positive and Gram-negative bacteria but is not cytotoxic towards human erythrocytes or protozoa.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_02571
- 2 Database:Uniprot P80571
- 3 Database:AMD DEF1_MYTGA
- 4 Database:DEF DEF137
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L12A02572| From 1 To 39 E-value: 2e-18 Score: 82.8
GFGCPNNYQCHRHCKSIPGRCGGYCGGWHRLRCTCYRCG - 2. L03A000031 From 1 To 39 E-value: 2e-17 Score: 79.7
GFGCPNNYQCHRHCKSIPGRCGGYCGGWHRLRCTCYRCG - 3. L01A003021 From 1 To 38 E-value: 5e-17 Score: 78.2
GFGCPNNYQCHRHCKSIPGRCGGYCGGWHRLRCTCYRC - 4. L02A000438 From 1 To 39 E-value: 9e-17 Score: 77.4
GFGCPNNYQCHRHCKSIPGRCGGYCGGWHRLPCTCYRCG - 5. L03A000030 From 1 To 37 E-value: 0.000000000000002 Score: 73.2
GFGCPNDYPCHRHCKSIPGRCGGYCGGWHRLRCTCYR
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Roch P.,Noeel T.,Hubert F.,
- Title:
- Journal:Eur. J. Biochem., 1996, 240, 815-815 [:]
- [2] Roch P.,Noeel T.,Hubert F.,
- Title:A member of the arthropod defensin family from edible Mediterranean mussels (Mytilus galloprovincialis).
- Journal:Eur. J. Biochem., 1996, 240, 302-306 [MEDLINE:97025339]
- [3] Roch P.,Hubert F.,Vandenbulcke F.,Mitta G.,
- Title:Mussel defensins are synthesised and processed in granulocytes then released into the plasma after bacterial challenge.
- Journal:J. Cell Sci., 1999, 112, 4233-4242 [MEDLINE:20033584]
- [4] Sanchez J.F.,Calas B.,Chavanieu A.,Mitta G.,Yang Y.S.,
- Title:Solution structure and activity of the synthetic four-disulfide bond Mediterranean mussel defensin (MGD-1).
- Journal:Biochemistry, 2000, 39, 14436-14447 [MEDLINE:20541401]
Comments
- Comments
No comments found on LAMP database