Record in detail


General Info

  • lamp_id:L03A000048
  • Name:DMS5_PHYBI
  • FullName:Dermaseptin-B5
  • Source:Phyllomedusa bicolor
  • Mass:2633.1 Da
  • Sequence Length:25 aa
  • Isoelectric Point:10.33
  • Activity:Antimicrobial
  • Sequence
        GLWNKIKEAAKSAGKAALGFVNEMV
  • Function:Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure.

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  P81487
  •   2  Database:AMD  DMS5_PHYBI

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000048    From 1 To 25 E-value: 0.00000001 Score: 50.4
        GLWNKIKEAAKSAGKAALGFVNEMV
  • 2. L13A025397    From 1 To 25 E-value: 0.0000001 Score: 47
        GLWSKIKEAAKTAGKAAMGFVNEMV
  • 3. L13A011220    From 1 To 25 E-value: 0.0000001 Score: 47
        GLWSKIKEAAKTAGKAAMGFVNEMV
  • 4. L01A002484    From 24 To 48 E-value: 0.0000006 Score: 44.7
        GLWSKIKEAAKTAGKMAMGFVNDMV
  • 5. L02A000940    From 1 To 25 E-value: 0.0000008 Score: 44.3
        GLWSKIKEAAKTAGKMAMGFVNDMV

Structure

  •   Domains
  •   1  Name:Dermaseptin    Interpro Link:IPR022731
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Le Caer J.-P.,Vouille V.,Mester J.,Amiche M.,Charpentier S.,
  •   Title:Structure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics.
  •   Journal:J. Biol. Chem., 1998, 273, 14690-14697  [MEDLINE:98278974]

Comments

  •   Comments

    •     No comments found on LAMP database



CAPTCHA Image   Reload Image
Enter Code*: