Record in detail
General Info
- lamp_id:L03A000069
- Name:DEFB3_BOVIN
- FullName:Beta-defensin 3
- Source:Bos taurus
- Mass:6324.5 Da
- Sequence Length:57 aa
- Isoelectric Point:11.71
- Activity:Antimicrobial
- Sequence
LALLFLVLSAGSGFTQGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW - Function:Has bactericidal activity. Active against E.coli ML35 and S.aureus 502A.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_05607
- 2 Database:Uniprot P46161
- 3 Database:AMD BD03_BOVIN
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000069 From 1 To 57 E-value: 3e-28 Score: 115
LALLFLVLSAGSGFTQGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW - 2. L12A09073| From 8 To 64 E-value: 5e-28 Score: 114
LALLFLVLSAGSGFTQGARNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW - 3. L03A000068 From 1 To 55 E-value: 5e-23 Score: 98.2
LALLFLVLSAGSGFTQGVRNFVTCRINRGFCVPIRCPGHRRQIGTCLAPQIKCCR - 4. L12A10105| From 7 To 61 E-value: 1e-21 Score: 93.6
LALLFLVLYAGSGFTQGVRNFVTCRINRGFCLPIRCPGHSRQIGTCLALQIKCCR - 5. L12A02363| From 1 To 44 E-value: 4e-21 Score: 91.7
FTQGVRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Novotny M.J.,McGuire P.A.,Morris W.L.,Tang Y.-Q.,Selsted M.E.,
- Title:Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
- Journal:J. Biol. Chem., 1993, 268, 6641-6648 [MEDLINE:93203264]
- [2] Erdjument-Bromage H.,Russell J.P.,Diamond G.,Clark D.P.,Tarver A.P.,
- Title:Enteric beta-defensin: molecular cloning and characterization of a gene with inducible intestinal epithelial cell expression associated with Cryptosporidium parvum infection.
- Journal:Infect. Immun., 1998, 66, 1045-1056 [MEDLINE:98147718]
Comments
- Comments
No comments found on LAMP database