Record in detail


General Info

  • lamp_id:L03A000078
  • Name:DMS2_AGAAN
  • FullName:Dermaseptin AA-2-5
  • Source:Agalychnis annae
  • Mass:7854.8 Da
  • Sequence Length:73 aa
  • Isoelectric Point:4.02
  • Activity:Antimicrobial
  • Sequence
        MAFLKKSLFLVLFLAIVPLSICEEEKREEENEEKQEDDDQSEKRGLVSGLLNTAGGLLGDLLGSLGSLSGGES
  • Function:Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  O93222
  •   2  Database:AMD  DMS2_AGAAN

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000078    From 1 To 73 E-value: 3e-35 Score: 138
        MAFLKKSLFLVLFLAIVPLSICEEEKREEENEEKQEDDDQSEKRGLVSGLLNTAGGLLGDLLGSLGSLSGGES
  • 2. L12A06177|    From 1 To 71 E-value: 0.000000000008 Score: 60.8
        MAFLKKSLFLVLFLGFVSVSICEEEKRQEDEDEHVEEGENQEEGSEEKRGLLSVLGSVAKHVLPHVVPVIA
  • 3. L12A06203|    From 1 To 54 E-value: 0.00000000005 Score: 58.2
        MAFMKKSLFLVLFLGMVSLSICEEEKRENEDEAKQEDDEQSEMKRGLWSTIKNV
  • 4. L12A06176|    From 1 To 67 E-value: 0.00000001 Score: 50.4
        MAFLKKSLFLGLFLGFVSVSICEEEKRQEDEDEHDEEGENQEEGSEEKRGLLSVLGSVAKHVLPHVV
  • 5. L03A000080    From 1 To 71 E-value: 0.00000002 Score: 49.3
        MAFLKKSLFLVLFLGLVPLFLCENEKREGENEKEENDDQSEEKRSLGSFMKGVGKGLATVGKIVADQFGKL

Structure

  •   Domains
  •   1  Name:Brevinin    Interpro Link:IPR004275
  •   2  Name:Dermaseptin_precursor    Interpro Link:IPR016322
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Wechselberger C.
  •   Title:Cloning of cDNAs encoding new peptides of the dermaseptin-family.
  •   Journal:Biochim. Biophys. Acta, 1998, 1388, 279-283  [MEDLINE:98449786]

Comments

  •   Comments

    •     No comments found on LAMP database



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