Record in detail
General Info
- lamp_id:L03A000079
- Name:DMS4_PACDA
- FullName:Dermaseptin PD-3-6
- Source:Pachymedusa dacnicolor
- Mass:7780.8 Da
- Sequence Length:71 aa
- Isoelectric Point:4.25
- Activity:Antimicrobial
- Sequence
MAFLKKSLFLVLFLALVPLSICEAEKREEENEEKQEDDDESEKKRGVVTDLLNTAGGLLGNLVGSLSGGER - Function:Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).
Cross-Linking
- Cross-linking
- 1 Database:Uniprot O93454
- 2 Database:AMD DMS4_PACDA
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000079 From 1 To 71 E-value: 5e-35 Score: 137
MAFLKKSLFLVLFLALVPLSICEAEKREEENEEKQEDDDESEKKRGVVTDLLNTAGGLLGNLVGSLSGGER - 2. L03A000078 From 1 To 54 E-value: 0.0000000000004 Score: 65.1
MAFLKKSLFLVLFLAIVPLSICEEEKREEENEEKQEDDDQSE-KRGLVSGLLNTA - 3. L12A06177| From 1 To 71 E-value: 0.00000000001 Score: 60.5
MAFLKKSLFLVLFLGFVSVSICEEEKRQEDEDEHVEEGENQEEGSEEKRGLLSVLGSVAKHVLPHVVPVIA - 4. L12A06203| From 1 To 54 E-value: 0.00000000002 Score: 59.3
MAFMKKSLFLVLFLGMVSLSICEEEKRENEDEAKQEDDEQSEMKRGLWSTIKNV - 5. L12A06176| From 1 To 71 E-value: 0.00000002 Score: 49.7
MAFLKKSLFLGLFLGFVSVSICEEEKRQEDEDEHDEEGENQEEGSEEKRGLLSVLGSVAKHVLPHVVPVIA
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Wechselberger C.
- Title:Cloning of cDNAs encoding new peptides of the dermaseptin-family.
- Journal:Biochim. Biophys. Acta, 1998, 1388, 279-283 [MEDLINE:98449786]
Comments
- Comments
No comments found on LAMP database