Record in detail
General Info
- lamp_id:L03A000080
- Name:DMS1_PACDA
- FullName:Dermaseptin PD-1-5
- Source:Pachymedusa dacnicolor
- Mass:8463.8 Da
- Sequence Length:77 aa
- Isoelectric Point:5.15
- Activity:Antimicrobial
- Sequence
MAFLKKSLFLVLFLGLVPLFLCENEKREGENEKEENDDQSEEKRSLGSFMKGVGKGLATVGKIVADQFGKLLEAGKG - Function:Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).
Cross-Linking
- Cross-linking
- 1 Database:Uniprot O93451
- 2 Database:AMD DMS1_PACDA
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000080 From 1 To 77 E-value: 3e-38 Score: 148
MAFLKKSLFLVLFLGLVPLFLCENEKREGENEKEENDDQSEEKRSLGSFMKGVGKGLATVGKIVADQFGKLLEAGKG - 2. L03A000081 From 1 To 77 E-value: 0.00000000000001 Score: 70.5
MAFLKKSLFLVLFLGLVPLSLCESEKREGENEEEQEDDQSEEKRSLGSFLKGVGTTLASVGKVVSDQFGKLLQAGQG - 3. L02A000908 From 1 To 33 E-value: 0.000000000001 Score: 63.5
SLGSFMKGVGKGLATVGKIVADQFGKLLEAGKG - 4. L02A000907 From 1 To 33 E-value: 0.000000000003 Score: 62.4
SLGSFMKGVGKGLATVGKIVADQFGKLLEAGQG - 5. L12A06177| From 1 To 75 E-value: 0.00000000003 Score: 59.3
MAFLKKSLFLVLFLGFVSVSICEEEKRQEDEDEHVEEGENQEEGSEEKRGLLSVLGSVAKHVLPHVVPVIAEHLG
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Wechselberger C.
- Title:Cloning of cDNAs encoding new peptides of the dermaseptin-family.
- Journal:Biochim. Biophys. Acta, 1998, 1388, 279-283 [MEDLINE:98449786]
Comments
- Comments
No comments found on LAMP database