Record in detail


General Info

  • lamp_id:L03A000084
  • Name:DMS3_PACDA
  • FullName:Dermaseptin PD-3-3
  • Source:Pachymedusa dacnicolor
  • Mass:8716.8 Da
  • Sequence Length:80 aa
  • Isoelectric Point:4.72
  • Activity:Antimicrobial
  • Sequence
        MAFLKKSLFLVLFLGLVSLSICEEKRENEDEEEQEDDEQSEEKRGMWSKIKNAGKAAAKASKKAAGKAALGAVSEALGEQ
  • Function:Possesses a potent antimicrobial activity against Gram-positive and Gram-negative bacteria. Probably acts by disturbing membrane functions with its amphipathic structure (By similarity).

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  O93453
  •   2  Database:AMD  DMS3_PACDA

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000084    From 1 To 80 E-value: 2e-39 Score: 152
        MAFLKKSLFLVLFLGLVSLSICEEKRENEDEEEQEDDEQSEEKRGMWSKIKNAGKAAAKASKKAAGKAALGAVSEALGEQ
  • 2. L12A06203|    From 1 To 56 E-value: 4e-16 Score: 75.1
        MAFMKKSLFLVLFLGMVSLSICEEEKRENEDEAKQEDDEQSEMKRGLWSTIKNVGK
  • 3. L12A06177|    From 1 To 62 E-value: 0.0000000000002 Score: 65.9
        MAFLKKSLFLVLFLGFVSVSICEEEKRQEDEDEHVEEGENQEEGSEEKRGLLSVLGSVAKHV
  • 4. L12A05358|    From 1 To 68 E-value: 0.000000000002 Score: 62.8
        KSLFLVLFLGMVSLSICEEEKRENEDEEKQEDDEQSEMKRGLWSTIKNVGKEAA----IAAGKAVLG----SLGEQ
  • 5. L12A06199|    From 1 To 56 E-value: 0.000000000003 Score: 62.4
        MAFLKKSLFLVLFLGMVSLSICEEEKRENEDEELQEDDEQSEMKRGLWSTIKNVGK

Structure

  •   Domains
  •   1  Name:Brevinin    Interpro Link:IPR004275
  •   2  Name:Dermaseptin    Interpro Link:IPR022731
  •   3  Name:Dermaseptin_precursor    Interpro Link:IPR016322
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Wechselberger C.
  •   Title:Cloning of cDNAs encoding new peptides of the dermaseptin-family.
  •   Journal:Biochim. Biophys. Acta, 1998, 1388, 279-283  [MEDLINE:98449786]

Comments

  •   Comments

    •     No comments found on LAMP database



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