Record in detail

lamp_id:L03A000092
Name:DEF2_RAPSA
FullName:Defensin-like protein 2
Source:Raphanus sativus
Mass:8875.4 Da
Sequence Length:80 aa
Isoelectric Point:8.41
Activity:Antimicrobial
Sequence
MAKFASIIVLLFVALVVFAAFEEPTMVEAQKLCQRPSGTWSGVCGNNNACKNQCIRLEKARHGSCNYVFPAHKCICYFPC
Function:Possesses antifungal activity sensitive to inorganic cations. Induces potential changes in fungal membranes and increased K(+) efflux and Ca(2+) uptake.

Top similar AMPs on LAMP
1. L03A000092 From 1 To 80 E-value: 7.9874e-44 Score: 167
MAKFASIIVLLFVALVVFAAFEEPTMVEAQKLCQRPSGTWSGVCGNNNACKNQCIRLEKARHGSCNYVFPAHKCICYFPC
2. L12A06263| From 1 To 80 E-value: 8.00001e-41 Score: 157
MAKFASIIALLFAALVLFAAFEAPTMVEAQKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
3. L01A002125 From 1 To 80 E-value: 5e-40 Score: 154
MAKFASIIALLFAALVLFAAFEAETMVEAQKLCERPSGTWSGVCGNNNACKNQCINLEKARHGSCNYVFPAHKCICYFPC
4. L03A000091 From 1 To 79 E-value: 6e-38 Score: 147
MAKFASIITLLFAALVVFAAFEAPTMVEA-KLCERSSGTWSGVCGNNNACKNQCIRLEGAQHGSCNYVFPAHKCICYFPC
5. L03A000090 From 1 To 80 E-value: 3e-37 Score: 145
MAKFASIIALLFAALVLFSAFEAPSMVEAQKLCEKSSGTWSGVCGNNNACKNQCINLEGARHGSCNYIFPYHRCICYFPC

Reference
[1] Rees S.B.,van Leuven F.,de Bolle M.F.C.,Schoofs H.M.E.,Terras F.R.G.,
Title:Analysis of two novel classes of plant antifungal proteins from radish (Raphanus sativus L.) seeds.
Journal:J. Biol. Chem., 1992, 267, 15301-15309 [MEDLINE:92348373]
[2] Osborn R.W.,Raikhel N.V.,Kovaleva V.,Eggermont K.,Terras F.R.G.,
Title:Small cysteine-rich antifungal proteins from radish: their role in host defense.
Journal:Plant Cell, 1995, 7, 573-588 [MEDLINE:95299350]
[3] Osborn R.W.,Brownlee C.,De Samblanx G.W.,Ghazi A.,Thevissen K.,
Title:Fungal membrane responses induced by plant defensins and thionins.
Journal:J. Biol. Chem., 1996, 271, 15018-15025 [PubMed:8663029]
[4] Fant F.,Raemaekers R.,Thevissen K.,Goderis I.J.,De Samblanx G.W.,
Title:Mutational analysis of a plant defensin from radish (Raphanus sativus L.) reveals two adjacent sites important for antifungal activity.
Journal:J. Biol. Chem., 1997, 272, 1171-1179 [PubMed:8995418]