Record in detail
General Info
- lamp_id:L03A000097
- Name:AMP2_MIRJA
- FullName:Antimicrobial peptide 2
- Source:Mirabilis jalapa
- Mass:6842.1 Da
- Sequence Length:63 aa
- Isoelectric Point:8.62
- Activity:Antimicrobial
- Sequence
MAKVPIAFLKFVIVLILFIAMSGMIEACIGNGGRCNENVGPPYCCSGFCLRQPNQGYGVCRNR - Function:Possesses antifungal activity and is also active on two tested Gram-positive bacteria but is non-toxic for Gram-negative bacteria and cultured human cells.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_06291
- 2 Database:Uniprot P25404
- 3 Database:AMD AMP2_MIRJA
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000097 From 1 To 63 E-value: 5e-32 Score: 127
MAKVPIAFLKFVIVLILFIAMSGMIEACIGNGGRCNENVGPPYCCSGFCLRQPNQGYGVCRNR - 2. L03A000073 From 1 To 61 E-value: 4e-26 Score: 108
LPVAFLKFAIVLILFIAMSAMIEAQCIGNGGRCNENVGPPYCCSGFCLRQPGQGYGYCKNR - 3. L01A000209 From 1 To 36 E-value: 1e-16 Score: 77
CIGNGGRCNENVGPPYCCSGFCLRQPNQGYGVCRNR - 4. L03A000098 From 1 To 65 E-value: 2e-16 Score: 76.3
MAKVSSAYLKFALVMILLLSVISAVMSAGCIKNGGRCNASAGPPYCCSSYCFQIAGQSYGVCKNR - 5. L01A000208 From 2 To 37 E-value: 0.000000000000003 Score: 72
CIGNGGRCNENVGPPYCCSGFCLRQPGQGYGYCKNR
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] van Damme J.,Proost P.,Terras F.R.G.,de Bolle M.F.C.,Cammue B.P.A.,
- Title:Isolation and characterization of a novel class of plant antimicrobial peptides from Mirabilis jalapa L. seeds.
- Journal:J. Biol. Chem., 1992, 267, 2228-2233 [MEDLINE:92129292]
- [2] Terras F.R.G.,Osborn R.W.,Duncan R.E.,Eggermont K.,de Bolle M.F.,
- Title:Cloning and characterization of two cDNA clones encoding seed-specific antimicrobial peptides from Mirabilis jalapa L.
- Journal:Plant Mol. Biol., 1995, 28, 713-721 [MEDLINE:95375234]
Comments
- Comments
No comments found on LAMP database