Record in detail


General Info

  • lamp_id:L03A000115
  • Name:ES1B_RANES
  • FullName:Esculentin-1B
  • Source:Rana esculenta
  • Mass:9132.9 Da
  • Sequence Length:84 aa
  • Isoelectric Point:8.92
  • Activity:Antimicrobial
  • Sequence
        MFTLKKPLLLIVLLGMISLSLCEQERNADEEEGSEIKRGIFSKLAGKKLKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
  • Function:Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and hemolytic activity.

Cross-Linking

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000115    From 1 To 84 E-value: 3.00018e-42 Score: 162
        MFTLKKPLLLIVLLGMISLSLCEQERNADEEEGSEIKRGIFSKLAGKKLKNLLISGLKNVGKEVGMDVVRTGIDIAGCKIKGEC
  • 2. L12A06987|    From 1 To 84 E-value: 2e-36 Score: 142
        MFTLKKPLLLIVLLGMISLSLCEQERAADEDVGNEIKRGIFSKISGKAIKNLFIKGAKNVGKEVGMDVVRTGIDVVGCKIKGEC
  • 3. L12A07030|    From 1 To 84 E-value: 3e-35 Score: 138
        MFTLKKSLLLIVLLGTISLSLCEQERAADEDEGNEIKRGLFSKFAGKGIKNFLIKGVKHIGKEVGMDVIRTGIDVAGCKIKGEC
  • 4. L12A07217|    From 1 To 83 E-value: 9e-35 Score: 137
        MFTMKKPLLL-VLLGIISLSLCEQERAADEDEGSEIKRGLFSKFAGKGIKNLIFKGVKNIGKEVGMDVIRTGIDVAGCKIKGEC
  • 5. L12A07216|    From 1 To 83 E-value: 1e-34 Score: 136
        MFTMKKPLLL-VLLGIISLSLCEQERAADEDEGSEIKRGLFSKFAGKGIKNFLIKGVKHIGKEVGMDVIRTGIDVAGCKIKGEC

Structure

  •   Domains
  •   1  Name:Antimicrobial_frog_2    Interpro Link:IPR012521
  •   2  Name:Brevinin    Interpro Link:IPR004275
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

  •     No MICs found on LAMP database

Toxicity

  •   Toxicity

  •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Bossa F.,Barra D.,Mignogna G.,Simmaco M.,
  •   Title:Antimicrobial peptides from skin secretions of Rana esculenta. Molecular cloning of cDNAs encoding esculentin and brevinins and isolation of new active peptides.
  •   Journal:J. Biol. Chem., 1994, 269, 11956-11961  [MEDLINE:94216303]

Comments

  •   Comments

  •     No comments found on LAMP database



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