Record in detail
General Info
- lamp_id:L03A000118
- Name:BR1E_RANES
- FullName:Brevinin-1E
- Source:Rana esculenta
- Mass:8266.5 Da
- Sequence Length:71 aa
- Isoelectric Point:4.63
- Activity:Antimicrobial
- Sequence
MFTLKKSMLLLFFLGTINLSLCEEERDADEEERRDNPDESEVEVEKRFLPLLAGLAANFLPKIFCKITRKC - Function:Shows antibacterial activity against representative Gram-negative and Gram-positive bacterial species, and a very high hemolytic activity.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_07166
- 2 Database:Uniprot P32412
- 3 Database:AMD BR1E_RANES
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000118 From 1 To 71 E-value: 5e-36 Score: 141
MFTLKKSMLLLFFLGTINLSLCEEERDADEEERRDNPDESEVEVEKRFLPLLAGLAANFLPKIFCKITRKC - 2. L12A07168| From 1 To 71 E-value: 3e-32 Score: 129
MFTLKKSMLLLFFLGTINLSLCEQERNADEEERRDNPDEMDVVVEKRFLPLLAGLAANFLPQIICKIARKC - 3. L01A003834 From 1 To 71 E-value: 3e-31 Score: 125
MFTFKKSMLLLFFLGTINLSLCEQERNADEEERRDDPDETNVEVEKRFLPLLAGVVANFLPQIICKIARKC - 4. L12A07293| From 1 To 71 E-value: 1e-27 Score: 113
MFTMKKSLLLLFFLGTINLSLCEQERNADEEERRDDPDERDVEVEKRFLPLIASLAANFVPKIFCKITKKC - 5. L12A07071| From 1 To 70 E-value: 3e-26 Score: 108
MFTLKKSLLLLFFLGTINLSLCEQERDADEEERRDDPDERDVEVEKRFLPLLAGLAANFLPKLFCKITRK
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Bossa F.,Barra D.,Mignogna G.,Simmaco M.,
- Title:Novel antimicrobial peptides from skin secretion of the European frog Rana esculenta.
- Journal:FEBS Lett., 1993, 324, 159-161 [MEDLINE:93285327]
- [2] Bossa F.,Barra D.,Mignogna G.,Simmaco M.,
- Title:Antimicrobial peptides from skin secretions of Rana esculenta. Molecular cloning of cDNAs encoding esculentin and brevinins and isolation of new active peptides.
- Journal:J. Biol. Chem., 1994, 269, 11956-11961 [MEDLINE:94216303]
Comments
- Comments
No comments found on LAMP database