Record in detail
General Info
- lamp_id:L03A000119
- Name:GGN4_GLARU
- FullName:Gaegurin-4
- Source:Glandirana rugosa
- Mass:8695 Da
- Sequence Length:80 aa
- Isoelectric Point:4.79
- Activity:Antimicrobial
- Sequence
MFTMKKSLLFLFFLGTISLSLCEEERSADEDDGGEMTEEEVKRGILDTLKQFAKGVGKDLVKGAAQGVLSTVSCKLAKTC - Function:Has a non-hemolytic activity. Has a broad spectrum of activity against both Gram-positive and Gram-negative bacteria, fungi and protozoa.
Cross-Linking
- Cross-linking
- 1 Database:dbAMP dbAMP_07242
- 2 Database:Uniprot P80398
- 3 Database:AMD GAE4_RANRU
Top similar AMPs
- Top similar AMPs on LAMP
- 1. L03A000119 From 1 To 80 E-value: 9.99995e-41 Score: 156
MFTMKKSLLFLFFLGTISLSLCEEERSADEDDGGEMTEEEVKRGILDTLKQFAKGVGKDLVKGAAQGVLSTVSCKLAKTC - 2. L01A003830 From 1 To 74 E-value: 5e-26 Score: 108
MFTSKKSLLVLFFLGTISLSFCEEERNADEDD-GEMT-EEVKRGILDTLKEF----GKTAAKGIAQSLLSTASCKLAKTC - 3. L12A07339| From 1 To 76 E-value: 9e-25 Score: 103
MFTMKKSLLVLFFLGTISLSLCQEERNADEEDGGEATEEEVKRSFLTTFKDLAIKAA----KSAGQSVLSTLSCKLSNTC - 4. L12A07231| From 1 To 75 E-value: 3e-24 Score: 102
MFTMKKSLLFLFFLGTISLSFCEEERSADEDDEGEMTEEE-KRSIRDKIKTIA----IDLAKGAGTGVLKTLICKLDKSC - 5. L12A07224| From 1 To 80 E-value: 5e-24 Score: 101
MFTMKKSILVLFFLGTISLSLCEQERSADEDDGEEIKEEEVKRGIFSLFKTAAKFVGKNLLKEAGKAGLEHLACKVKNEC
Activity
- Antibacterial Activities
No MICs found on LAMP database
Toxicity
- Toxicity
No toxicity records found on LAMP database
Reference
- Reference
- [1] Lee B.J.,Jung J.-E.,Park J.M.,
- Title:Antimicrobial peptides from the skin of a Korean frog, Rana rugosa.
- Journal:Biochem. Biophys. Res. Commun., 1994, 205, 948-954 [MEDLINE:95091844]
- [2] Lee B.J.,Park J.M.,Carlson B.A.,Kwon S.Y.,
- Title:Structural organization and expression of the gaegurin 4 gene of Rana rugosa.
- Journal:Biochim. Biophys. Acta, 2000, 1492, 185-190 [MEDLINE:20461774]
- [3] Park Y.H.,Lee S.H.,Kim D.H.,Kim J.S.,Chi S.W.,
- Title:Solution structure and membrane interaction mode of an antimicrobial peptide gaegurin 4.
- Journal:Biochem. Biophys. Res. Commun., 2007, 352, 592-597 [PubMed:17141187]
Comments
- Comments
No comments found on LAMP database