Record in detail


General Info

  • lamp_id:L03A000126
  • Name:PFPN_ENTHI
  • FullName:Non-pathogenic pore-forming peptide
  • Source:Entamoeba histolytica
  • Mass:10432.3 Da
  • Sequence Length:97 aa
  • Isoelectric Point:7.76
  • Activity:Antimicrobial
  • Sequence
        MKAIVFVLIFAVAFAVTLRQGPIVCNLCTGLINTLENLLTTKGADKVKDYIDSLCNKASGFIATLCTKVLDFGVDKLIQLIEDKVDANAICAKIHAC
  • Function:Forms pores in the membrane of host tissues. Implicated in the cytolytic activity of the parasite.

Cross-Linking

  •   Cross-linking
  •   1  Database:Uniprot  Q07831
  •   2  Database:AMD  ENTA_ENTDI

Top similar AMPs

  • Top similar AMPs on LAMP
  • 1. L03A000126    From 1 To 97 E-value: 0 Score: 191
        MKAIVFVLIFAVAFAVTLRQGPIVCNLCTGLINTLENLLTTKGADKVKDYIDSLCNKASGFIATLCTKVLDFGVDKLIQLIEDKVDANAICAKIHAC
  • 2. L03A000125    From 1 To 98 E-value: 0 Score: 176
        MKAIVFVLIFAVAFAVTATHQGEILCNLCTGLINTLENLLTTKGADKVKDYISSLCNKASGFIATLCTKVLDFGIDKLIQLIEDKVDANAICAKIHAC
  • 3. L01A000511    From 1 To 77 E-value: 8e-38 Score: 147
        GEILCNLCTGLINTLENLLTTKGADKVKDYISSLCNKASGFIATLCTKVLDFGIDKLIQLIEDKVDANAICAKIHAC
  • 4. L03A000240    From 1 To 96 E-value: 3e-31 Score: 125
        MRAIVFVLIFAIAFAAT-REGSILCNLCKDTVNLIENLLTVDGAQAVRQYIDNLCAKADGFLGTLCNKILSFGVDELVKLIENHVDPVVICEKIHAC
  • 5. L03A000239    From 1 To 96 E-value: 7e-31 Score: 124
        MRAIIFVLIFAIAFAAT-REGAILCNLCKDTVKLVENLLTVDGAQAVRQYIDNLCGKASGFLGTLCEKILSFGVDELVKLIENHVDPVVVCEKIHAC

Structure

  •   Domains
  •   1  Name:SapB_1    Interpro Link:IPR007856
  •   2  Name:SapB_2    Interpro Link:IPR008138
  •   3  Name:Saposin-like    Interpro Link:IPR011001
  •   4  Name:SaposinB    Interpro Link:IPR008139
  •   Structures

        No structs found on LAMP database

Activity

  •   Antibacterial Activities

    •     No MICs found on LAMP database

Toxicity

  •   Toxicity

    •     No toxicity records found on LAMP database

Reference

  •   Reference
  •   [1]  Horstmann R.D.,Tannich E.,Bahr E.,Leippe M.,
  •   Title:Comparison of pore-forming peptides from pathogenic and nonpathogenic Entamoeba histolytica.
  •   Journal:Mol. Biochem. Parasitol., 1993, 59, 101-110  [MEDLINE:93295428]

Comments

  •   Comments

    •     No comments found on LAMP database



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