Record in detail

lamp_id:L03A000127
Name:DEFL1_CENLL
FullName:Defensin-1
Source:Centruroides limpidus limpidus
Mass:6395.6 Da
Sequence Length:56 aa
Isoelectric Point:8.27
Activity:Antimicrobial
Sequence
MKAIVVLLILALILCLYAMTTVEGACQFWSCNSSCISRGYRQGYCWGIQYKYCQCQ
Function:Antibacterial protein involved in the immune response to septic injury. When combined with 14.026 kDa and 14.059 kDa hemolymph antimicrobial peptides, it has a strong cooperative activity against the Gram-positive bacteria B.subtilis and S.aureus, and against the Gram-negative bacteria E.coli DH5-alpha and K.pneumoniae ATCC 138833. No detectable antibacterial activity when present alone. Has no hemolytic activity in human erythrocytes.

Top similar AMPs on LAMP
1. L03A000127 From 1 To 56 E-value: 1e-27 Score: 113
MKAIVVLLILALILCLYAMTTVEGACQFWSCNSSCISRGYRQGYCWGIQYKYCQCQ
2. L05ADEF128 From 1 To 32 E-value: 0.00000000000003 Score: 68.9
ACQFWSCNSSCISRGYRQGYCWGIQYKYCQCQ
3. L12A07775| From 1 To 52 E-value: 0.015 Score: 30
MKAVYFVFLLVAALA---YFTSNVAAACNDRDCSLDCIMKGYNTGSCV---RGSCQCR
4. L01A002430 From 1 To 47 E-value: 0.032 Score: 28.9
MKAVFVLLVVGLCIMMMDVATAGFGCPNNYACHQHCKSIRGYCGGYC
5. L13A012049 From 17 To 43 E-value: 0.037 Score: 28.9
DCNGECLLRGYKGGYCSGFANVNCWCE

Reference
[1] Scaloni A.,Diego-Garcia E.,D"Ambrosio C.,Garcia B.I.,Rodriguez De La Vega R.C.,
Title:Antimicrobial peptide induction in the haemolymph of the Mexican scorpion Centruroides limpidus limpidus in response to septic injury.
Journal:Cell. Mol. Life Sci., 2004, 61, 1507-1519 [PubMed:15197474]